Ferroptosis is a form of regulated cell death that is characterized by iron-dependent
oxidative damage and subsequent plasma membrane ruptures and the release of damage …

Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron
metabolism and accumulation of lipid peroxides. It features the alteration of mitochondria …

Epidemiological data indicate a constant worldwide increase in cancer mortality, although
the age of onset is increasing. Recent accumulation of genomic data on human cancer via …

Multiwalled carbon nanotubes (MWCNTs) have the potential for widespread applications in
engineering and materials science. However, because of their needle-like shape and high …

Hypoxia and acidity provide microenvironment for selection under evolutionary pressure
and proliferation in cancer cells. Carbonic anhydrases (CAs) are a superfamily of …

Highlights•The Biologically Effective Dose (BED) is the mechanistic entity that actually drives
toxicity.•Mechanisms of nanoparticle (NP) toxicity need to be considered in relation to …

Asbestos causes malignant transformation of primary human mesothelial cells (HM), leading
to mesothelioma. The mechanisms of asbestos carcinogenesis remain enigmatic, as …

Carbon nanotubes (CNTs) are nanomaterials with broad applications that are produced on
a large scale. Animal experiments have shown that exposure to CNTs, especially one type …

Asbestos-associated diseases remain a social burden worldwide. Our previous studies
identified asbestos-induced iron-rich milieu for mesothelial cells with ceaseless macrophage …

During the last two decades several nanoscale materials were engineered for industrial and
medical applications. Among them carbon nanotubes (CNTs) are the most exploited …