The most frequent and feared complication of paroxysmal nocturnal hemoglobinuria (PNH)
is thrombosis. Recent research has demonstrated that the complement and coagulation …

Lower-than-normal platelet counts are a hallmark of the acquired autoimmune illness known
as immune thrombocytopenia, which can affect both adults and children. Immune …

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and a
leading cause of death in the US and worldwide. HCC remains a global health problem and …

The role of the complement system in immune thrombocytopenic purpura (ITP) is not well
defined. We examined plasma from 79 patients with ITP, 50 healthy volunteers, and 25 …

Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by uncontrolled
activation of the terminal complement pathway, leading to intravascular hemolysis (IVH) and …

Sickle cell disease (SCD) is a common inherited clinical syndrome, characterized by the
presence of hemoglobin S. Anemia, susceptibility to infections and episodes of vaso …

Autoimmune hemolytic anemia (AIHA) is a rare autoimmune disease characterized by a
hemolytic anemia caused by autoantibodies against red blood cells (RBCs). These …

Sickle cell disease (SCD) is a widely spread inherited hemoglobinopathy that includes a
group of congenital hemolytic anemias, all characterized by the predominance of sickle …

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal hematopoietic stem
cell disorder caused by somatic mutations in the PIG-A gene, leading to the production of …

Background The procoagulant activity of tissue factor-bearing microvesicles (MV-TF) has
been associated with the risk of developing venous thrombosis in cancer patients. However …