Functional dental pulp regeneration: basic research and clinical translation

Z Xie, Z Shen, P Zhan, J Yang, Q Huang… - International journal of …, 2021 - mdpi.com
Pulpal and periapical diseases account for a large proportion of dental visits, the current
treatments for which are root canal therapy (RCT) and pulp revascularisation. Despite the …

Advances in antimicrobial hydrogels for dental tissue engineering: regenerative strategies for endodontics and periodontics

D Atila, V Kumaravel - Biomaterials Science, 2023 - pubs.rsc.org
Dental tissue infections have been affecting millions of patients globally leading to pain,
severe tissue damage, or even tooth loss. Commercial sterilizers may not be adequate to …

[HTML][HTML] Vascularized pulp regeneration via injecting simvastatin functionalized GelMA cryogel microspheres loaded with stem cells from human exfoliated deciduous …

X Yuan, Z Yuan, Y Wang, Z Wan, X Wang, S Yu… - Materials Today Bio, 2022 - Elsevier
Dental pulp necrosis are serious pathologic entities that causes tooth nutrition deficiency
and abnormal root development, while regeneration of functional pulp tissue is of paramount …

[HTML][HTML] Biomaterial scaffolds for clinical procedures in endodontic regeneration

H Liu, J Lu, Q Jiang, M Haapasalo, J Qian, FR Tay… - Bioactive Materials, 2022 - Elsevier
Regenerative endodontic procedures have been rapidly evolving over the past two decades
and are employed extensively in clinical endodontics. These procedures have been …

Microenvironment influences odontogenic mesenchymal stem cells mediated dental pulp regeneration

X Huang, Z Li, A Liu, X Liu, H Guo, M Wu… - Frontiers in …, 2021 - frontiersin.org
Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial
invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a …

Scaffold-based and scaffold-free strategies in dental pulp regeneration

WL Dissanayaka, C Zhang - Journal of endodontics, 2020 - Elsevier
Regenerative dentistry has come a long way from pulp capping to pulp regeneration
research, which aims to regenerate the pulp-dentin complex and restore its functions …

Fabrication and characterization of a novel injectable human amniotic membrane hydrogel for dentin-pulp complex regeneration

H Bakhtiar, MR Mousavi, S Rajabi… - Dental Materials, 2023 - Elsevier
Objective Injectable biomaterials that can completely fill the root canals and provide an
appropriate environment will have potential application for pulp regeneration in …

Engineering stem cell-derived extracellular matrices: decellularization, characterization, and biological function

S Sart, R Jeske, X Chen, T Ma, Y Li - Tissue Engineering Part B …, 2020 - liebertpub.com
Stem cells, including mesenchymal stem cells and pluripotent stem cells, have attracted
considerable attention in tissue engineering and regenerative medicine primarily because of …

Extracellular matrix derived from dental pulp stem cells promotes mineralization

N Nowwarote, S Petit, FC Ferre, F Dingli… - … in Bioengineering and …, 2022 - frontiersin.org
Background: Extracellular matrix (ECM) plays a pivotal role in many physiological
processes. ECM macromolecules and associated factors differ according to tissues, impact …

Towards a new concept of regenerative endodontics based on mesenchymal stem cell-derived secretomes products

LA Costa, N Eiro, A Vaca, FJ Vizoso - Bioengineering, 2022 - mdpi.com
The teeth, made up of hard and soft tissues, represent complex functioning structures of the
oral cavity, which are frequently affected by processes that cause structural damage that can …