Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …
environment and societal development. One of the most important pathogens responsible …
[HTML][HTML] A rulebook for peptide control of legume–microbe endosymbioses
Plants engage in mutually beneficial relationships with microbes, such as arbuscular
mycorrhizal fungi or nitrogen-fixing rhizobia, for optimized nutrient acquisition. In return, the …
mycorrhizal fungi or nitrogen-fixing rhizobia, for optimized nutrient acquisition. In return, the …
Evaluation of the Antimicrobial Activity in Host-Mimicking Media and In Vivo Toxicity of Antimicrobial Polymers as Functional Mimics of AMPs
Activity tests for synthetic antimicrobial compounds are often limited to the minimal inhibitory
concentration assay using standard media and bacterial strains. In this study, a family of …
concentration assay using standard media and bacterial strains. In this study, a family of …
Mastoparans: a group of multifunctional α-helical peptides with promising therapeutic properties
Biologically active peptides have been attracting increasing attention, whether to improve
the understanding of their mechanisms of action or in the search for new therapeutic drugs …
the understanding of their mechanisms of action or in the search for new therapeutic drugs …
An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections
K Rangel, GC Lechuga, DW Provance Jr, CM Morel… - Pharmaceuticals, 2023 - mdpi.com
The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …
global health. The World Health Organization (WHO) has recognized the urgent need to …
Peptides as a therapeutic strategy against Klebsiella pneumoniae
CM de Souza, ÁP da Silva, NGO Júnior… - Trends in …, 2022 - cell.com
Increasing levels of resistance to conventional antibiotics have led to a search for new
therapeutic options against bacterial infections. Klebsiella pneumoniae is considered a …
therapeutic options against bacterial infections. Klebsiella pneumoniae is considered a …
AtGCS promoter-driven clustered regularly interspaced short palindromic repeats/Cas9 highly efficiently generates homozygous/biallelic mutations in the transformed …
S Liu, X Wang, Q Li, W Peng, Z Zhang, P Chu… - Frontiers in Plant …, 2022 - frontiersin.org
Agrobacterium rhizogenes–mediated (ARM) transformation is an efficient and powerful tool
to generate transgenic roots to study root-related biology. For loss-of-function studies …
to generate transgenic roots to study root-related biology. For loss-of-function studies …
Legume plant peptides as sources of novel antimicrobial molecules against human pathogens
Antimicrobial peptides are prominent components of the plant immune system acting against
a wide variety of pathogens. Legume plants from the inverted repeat lacking clade (IRLC) …
a wide variety of pathogens. Legume plants from the inverted repeat lacking clade (IRLC) …
Combining SNAPs with antibiotics shows enhanced synergistic efficacy against S. aureus and P. aeruginosa biofilms
Biofilm infections are associated with a high mortality risk for patients. Antibiotics perform
poorly against biofilm communities, so high doses and prolonged treatments are often used …
poorly against biofilm communities, so high doses and prolonged treatments are often used …
Unexplored arsenals of legume peptides with potential for their applications in medicine and agriculture
RM Lima, S Kylarová, P Mergaert… - Frontiers in …, 2020 - frontiersin.org
During endosymbiosis, bacteria live intracellularly in the symbiotic organ of their host. The
host controls the proliferation of endosymbionts and prevents their spread to other tissues …
host controls the proliferation of endosymbionts and prevents their spread to other tissues …