New insight into phytochromes: connecting structure to function

J Hughes, A Winkler - Annual review of plant biology, 2024 - annualreviews.org
Red and far-red light–sensing phytochromes are widespread in nature, occurring in plants,
algae, fungi, and prokaryotes. Despite at least a billion years of evolution, their photosensory …

Red light optogenetics in neuroscience

K Lehtinen, MS Nokia, H Takala - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …

Protein control of photochemistry and transient intermediates in phytochromes

G Salvadori, V Macaluso, G Pellicci, L Cupellini… - Nature …, 2022 - nature.com
Phytochromes are ubiquitous photoreceptors responsible for sensing light in plants, fungi
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …

Single-component near-infrared optogenetic systems for gene transcription regulation

AA Kaberniuk, M Baloban, MV Monakhov… - Nature …, 2021 - nature.com
Near-infrared (NIR) optogenetic systems for transcription regulation are in high demand
because NIR light exhibits low phototoxicity, low scattering, and allows combining with …

Individual and shared digital repertoires–older adults managing digital services

R Hänninen, L Pajula, V Korpela… - … Communication & Society, 2023 - Taylor & Francis
The rise of public and other non-recreational digital services is based on the idea of catering
to the daily needs of the citizens cost-efficiently and with ease. Previous research has …

Probing structure and reaction dynamics of proteins using time-resolved resonance Raman spectroscopy

D Buhrke, P Hildebrandt - Chemical reviews, 2019 - ACS Publications
The mechanistic understanding of protein functions requires insight into the structural and
reaction dynamics. To elucidate these processes, a variety of experimental approaches are …

Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

E Multamäki, R Nanekar, D Morozov… - Nature …, 2021 - nature.com
Bacterial phytochrome photoreceptors usually belong to two-component signaling systems
which transmit environmental stimuli to a response regulator through a histidine kinase …

Tips and turns of bacteriophytochrome photoactivation

H Takala, P Edlund, JA Ihalainen… - Photochemical & …, 2020 - pubs.rsc.org
Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction
and movement in plants, fungi and bacteria. Phytochromes switch between two …

[HTML][HTML] Cyanobacteriochromes from Gloeobacterales provide new insight into the diversification of cyanobacterial photoreceptors

NC Rockwell, JC Lagarias - Journal of Molecular Biology, 2024 - Elsevier
The phytochrome superfamily comprises three groups of photoreceptors sharing a
conserved GAF (cGMP-specific phosphodiesterases, cyanobacterial adenylate cyclases …

Bacteriophytochromes–from informative model systems of phytochrome function to powerful tools in cell biology

G Gourinchas, S Etzl, A Winkler - Current opinion in structural biology, 2019 - Elsevier
Highlights•Fluorescent probes or optogenetic tools can be developed using phytochrome
modules.•Bacteriophytochromes provide advantageous properties in protein engineering …