HIV-exposed uninfected children: a growing population with a vulnerable immune system?

L Afran, M Garcia Knight, E Nduati… - Clinical & …, 2014 - academic.oup.com
Through the successful implementation of policies to prevent mother-to-child-transmission
(PMTCT) of HIV-1 infection, children born to HIV-1-infected mothers are now much less likely …

Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes

E Villamor, WW Fawzi - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Vitamin A supplementation to preschool children is known to decrease the risks of mortality
and morbidity from some forms of diarrhea, measles, human immunodeficiency virus (HIV) …

[HTML][HTML] The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa

FO Ter Kuile, ME Parise, FH Verhoeff… - … Intolerable Burden of …, 2004 - ncbi.nlm.nih.gov
In sub-Saharan Africa, human immunodeficiency virus (HIV) and malaria are among the
leading causes of morbidity during pregnancy. We reviewed available information collected …

The immune system of HIV-exposed uninfected infants

B Abu-Raya, TR Kollmann, A Marchant… - Frontiers in …, 2016 - frontiersin.org
Infants born to human immunodeficiency virus (HIV) infected women are HIV-exposed but
the majority remains uninfected [ie, HIV-exposed uninfected (HEU)]. HEU infants suffer …

Children who are HIV-exposed and uninfected: evidence for action

AJ Prendergast, C Evans - Aids, 2023 - journals.lww.com
Prior to widespread availability of antiretroviral therapy (ART) in sub-Saharan Africa,
children who were HIV-exposed but uninfected (HEU) had increased mortality, morbidity …

Developmental immunology and role of host defenses in fetal and neonatal susceptibility to infection

DB Lewis, JH Weitkamp, O Levy - … and Klein's Infectious Diseases of the …, 2025 - Elsevier
The human fetus and neonate are unduly susceptible to infection with a number of bacterial,
fungal, protozoal, and viral agents, many of which are not pathogenic in older children and …

Severe infections in HIV-exposed uninfected infants: clinical evidence of immunodeficiency

AL Slogrove, MF Cotton… - Journal of tropical …, 2010 - academic.oup.com
We describe the clinical and basic immunological findings of eight HIV-exposed uninfected
infants hospitalized with serious infectious morbidity and referred for immunological …

High incidence of invasive group B streptococcal infections in HIV-exposed uninfected infants

C Epalza, T Goetghebuer, M Hainaut, F Prayez… - …, 2010 - publications.aap.org
OBJECTIVES: The occurrence of an unusual number of group B streptococcal (GBS)
infections in HIV-exposed uninfected (HEU) infants who were followed in our center …

Biological mechanisms of vertical human immunodeficiency virus (HIV‐1) transmission

DA Lehman, C Farquhar - Reviews in medical virology, 2007 - Wiley Online Library
In the absence of interventions, 30–45% of exposed infants acquire human
immunodeficiency virus type 1 (HIV‐1) through mother‐to‐child transmission. It remains …

Mother-to-child transmission of HIV: pathogenesis, mechanisms and pathways

AP Kourtis, M Bulterys - Clinics in perinatology, 2010 - perinatology.theclinics.com
Without doubt, one of the greatest medical and public health achievements has been the
significant reduction in mother-to-child transmission (MTCT) of human immunodeficiency …