HibeRNAtion: HIV-1 RNA metabolism and viral latency

R Crespo, S Rao, T Mahmoudi - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of
resting memory CD4+ T cells bearing replication-competent provirus. Pharmacological …

[HTML][HTML] The molecular mechanism and challenge of targeting XPO1 in treatment of relapsed and refractory myeloma

M Sellin, S Berg, P Hagen, J Zhang - Translational Oncology, 2022 - Elsevier
Multiple myeloma (MM) treatment regimens have vastly improved since the introduction of
immunomodulators, proteasome inhibitors, and anti-CD38 monoclonal antibodies; however …

Novel non-immunologic agents for relapsed and refractory multiple myeloma: a review article

A Bobin, C Gruchet, S Guidez, H Gardeney… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy-based treatments have brought many new options in the
treatment of multiple myeloma; still, the disease will inevitably relapse as it remains …

Efficacy and safety of selinexor-based regimens for relapsed/refractory multiple myeloma: a systematic review of literature

A Masood, Q Iqbal, H Ehsan, JA Davis, DK Hansen… - Annals of …, 2022 - Springer
With the incorporation of novel agents in earlier lines of therapy, an increasing number of
multiple myeloma patients are refractory to traditional classes of drugs. Selinexor in …

[PDF][PDF] 塞利尼索为基础方案治疗10 例复发难治多发性骨髓瘤疗效观察

李莹, 王耀美, 崔玉山, 房佰俊 - 临床血液学杂志, 2023 - lcxy.whuhzzs.com
目的: 观察塞利尼索治疗复发难治多发性骨髓瘤的疗效及不良反应. 方法: 回顾性分析河南省肿瘤
医院2021 年6 月—2022 年6 月采用塞利尼索治疗的10 例复发难治多发性骨髓瘤患者的临床 …

Efficacy of Selinexor in Relapsed/Refractory Multiple Myeloma (RRMM) Patients with del17p and Other High-Risk Abnormalities (A Retrospective Single-Center Study …

H Ehsan, M Robinson, PM Voorhees, K Cassetta… - Life, 2024 - mdpi.com
Selinexor (Seli) is a first-in-class, oral selective inhibitor of the nuclear export protein,
exportin-1 (XPO1). Seli exhibits its antitumor effect through the blockage of XPO1, which …

[HTML][HTML] Expert clinical framework report: Management of adverse events related to novel therapies for relapsed/refractory multiple myeloma (RRMM)

J Lacey, J Hewitt… - Canadian …, 2022 - canadianhematologytoday.com
Expert clinical framework report: Management of adverse events related to novel therapies for
relapsed/refractory multiple myeloma (RRMM) | Canadian Hematology Today Skip to main …

Efficacy observation of selinexor-based regimen in the treatment of 10 patients with relapsed/refractory multiple myeloma

LI Ying, W Yaomei, CUI Yushan, F Baijun - J Clin Hematol, 2023 - lcxyen.whuhzzs.com
Efficacy observation of selinexor-based regimen in the treatment of 10 patients with relapsed/refractory
multiple myeloma Homepage Journals 1.{{journal.titleEn}} {{journal.titleEn}} {{journal.titleEn}} …