Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Background Activities of daily living (ADLs) and instrumental activities of daily living (IADLs)
are essential for independent living and are predictors of morbidity and mortality in older …

Introduction: Loss of skeletal muscle mass and function (sarcopenia) is common in
individuals with obesity due to metabolic changes associated with a sedentary lifestyle …

Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

Objective To determine whether a multicomponent intervention based on physical activity
with technological support and nutritional counselling prevents mobility disability in older …

Thousands of Italians with coronavirus disease 2019 (COVID-19) have been admitted to
hospital. In the Piedmont Region, as of 12 May 2020, 12 272 patients survived hospital …

Importance The benefits of vitamin D, omega-3 fatty acids, and exercise in disease
prevention remain unclear. Objective To test whether vitamin D, omega-3s, and a strength …

Background Cellular senescence is a key mechanism that drives age-related diseases, but
has yet to be targeted therapeutically in humans. Idiopathic pulmonary fibrosis (IPF) is a …

Eight years have passed since the publication of the only guideline on cardiac rehabilitation
(CR) in Japan,“Guidelines for rehabilitation in patients with cardiovascular disease (JCS …

Frailty is a complex age-related clinical condition characterised by a decline in physiological
capacity across several organ systems, with a resultant increased susceptibility to stressors …