SARS-CoV-2 mutations: the biological trackway towards viral fitness

P Majumdar, S Niyogi - Epidemiology & Infection, 2021 - cambridge.org
The outbreak of pneumonia-like respiratory disorder at China and its rapid transmission
world-wide resulted in public health emergency, which brought lineage B betacoronaviridae …

Detection of respiratory viruses directly from clinical samples using next‐generation sequencing: A literature review of recent advances and potential for routine …

X Wang, S Stelzer‐Braid, M Scotch… - Reviews in Medical …, 2022 - Wiley Online Library
Acute respiratory infection is the third most frequent cause of mortality worldwide, causing
over 4.25 million deaths annually. Although most diagnosed acute respiratory infections are …

DIA-based proteome profiling of nasopharyngeal swabs from COVID-19 patients

DG Mun, PM Vanderboom… - Journal of Proteome …, 2021 - ACS Publications
Since the recent outbreak of COVID-19, there have been intense efforts to understand viral
pathogenesis and host immune response to combat SARS-CoV-2. It has become evident …

[HTML][HTML] Targeting some enzymes with repurposing approved pharmaceutical drugs for expeditious antiviral approaches against newer strains of COVID-19

SS Mohanty, CR Sahoo, RN Padhy - AAPS PharmSciTech, 2021 - Springer
At present, global vaccination for the SARS-CoV2 virus 2019 (COVID-19) is 95% effective.
Generally, viral infections are arduous to cure due to the mutating nature of viral genomes …

[HTML][HTML] Unlocking the puzzle: non-defining mutations in SARS-CoV-2 proteome may affect vaccine effectiveness

E Ulzurrun, A Grande-Pérez, D Del Hoyo… - Frontiers in Public …, 2024 - frontiersin.org
Introduction SARS-CoV-2 variants are defined by specific genome-wide mutations
compared to the Wuhan genome. However, non-clade-defining mutations may also impact …

COVID-19 Challenge: A Quest for Effective Vaccine Strategies Against Circulating and Emerging SARS-CoV-2 Variants

R Yogesh, N Srivastava… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Introduction: SARS-CoV-2 belongs to the coronavirus family, a large family of viruses
infecting avian and mammalian hosts. Accumulated mutations over time in the genome of …

[HTML][HTML] Evaluation of positive end-expiratory pressure strategies in patients with coronavirus disease 2019–induced acute respiratory distress syndrome

C Pan, C Lu, X She, H Ren, H Wei, L Xu… - Frontiers in …, 2021 - frontiersin.org
Background: Different positive end-expiratory pressure (PEEP) strategies are available for
subjects with coronavirus disease 2019 (COVID-19)–induced acute respiratory distress …

Proteomics and COVID-19: Recent Trends

C Chandarana, V Prajapati, V Vashi, J Patel - … : Recent Trends and …, 2024 - Springer
Proteomics has been found to be a helpful tool in understanding COVID-19 disease. It has
provided important insights into the complex interactions between the SARS-CoV-2 virus …

Microarrays and NGS for drug discovery

LA Pop, O Zanoaga, P Chiroi, A Nutu… - Drug Design-Novel …, 2021 - books.google.com
Novel technologies and state of the art platforms developed and launched over the last two
decades such as microarrays, next-generation sequencing, and droplet PCR have provided …

Vaccines against COVID-19–catching the rays of hope

SK Srinivasamurthy… - Journal of …, 2021 - asian.openbookpublished.com
COVID-19 pandemic has affected the world in all its dimensions. With herd immunity being a
distant and non-practical possibility, vaccination remains most tractable approach to reduce …