Human pharmaceuticals in the aquatic environment: a review of recent toxicological studies and considerations for toxicity testing

JM Brausch, KA Connors, BW Brooks… - Reviews of Environmental …, 2012 - Springer
Widespread detection of human pharmaceuticals in the environment, ranging between ng/L
and mg/L levels in surface waters and effluents and ng/kg to mg/kg levels in aquatic and …

Overview of a workshop on screening methods for detecting potential (anti‐) estrogenic/androgenic chemicals in wildlife

G Ankley, E Mihaich, R Stahl, D Tillitt… - … and Chemistry: An …, 1998 - Wiley Online Library
The US Congress has passed legislation requiring the US Environmental Protection Agency
(US EPA) to develop, validate, and implement screening tests for identifying potential …

Pharmaceuticals and personal care products in archived US biosolids from the 2001 EPA national sewage sludge survey

K McClellan, RU Halden - Water research, 2010 - Elsevier
In response to the US National Academies' call for a better assessment of chemical
pollutants contained in the approximately 7 million dry tons of digested municipal sludge …

Anticancer drugs in surface waters: what can we say about the occurrence and environmental significance of cytotoxic, cytostatic and endocrine therapy drugs?

JP Besse, JF Latour, J Garric - Environment international, 2012 - Elsevier
This study considers the implications and research needs arising from anticancer (also
referred to as antineoplastic) drugs being released into the aquatic environment, for the …

Pharmaceuticals in hospital wastewater: their ecotoxicity and contribution to the environmental hazard of the effluent

O Frédéric, P Yves - Chemosphere, 2014 - Elsevier
Nowadays, pharmaceuticals are found in every compartment of the environment. Hospitals
are one of the main sources of these pollutant emissions sent to wastewater treatment plants …

The need for water quality criteria for frogs.

R Boyer, CE Grue - Environmental health perspectives, 1995 - ehp.niehs.nih.gov
Amphibians are considered reliable indicators of environmental quality. In the western
United States, a general decline of frog populations parallels an apparent worldwide …

Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals

R Zounková, P Odráška, L Doležalová… - … and Chemistry: An …, 2007 - Wiley Online Library
The fate and effects of cytostatic (anticancer or antineoplastic) pharmaceuticals in the
environment are largely unknown, but they can contaminate wastewater treatment effluents …

Anuran development, density and diversity in relation to agricultural activity in the Holland River watershed, Ontario, Canada (1990–1992)

CA Bishop, NA Mahony, J Struger, P Ng… - Environmental Monitoring …, 1999 - Springer
Significantly lower anuran species diversity and density was recorded in a vegetable
growing area relative to upstream and downstream sites in the Holland River watershed …

Assessing caffeine as an emerging environmental concern using conventional approaches

MT Moore, SL Greenway, JL Farris… - Archives of environmental …, 2008 - Springer
Organic wastewater contaminants, including pharmaceuticals, caffeine, and nicotine, have
received increased scrutiny because of their detection in water bodies receiving wastewater …

Chronic toxicity of environmental contaminants: sentinels and biomarkers.

GA LeBlanc, LJ Bain - Environmental Health Perspectives, 1997 - ehp.niehs.nih.gov
Due to the use of a limited number of species and subchronic exposures, current ecological
hazard assessment processes can underestimate the chronic toxicity of environmental …