[HTML][HTML] Control of human toxoplasmosis

NC Smith, C Goulart, JA Hayward, A Kupz… - International journal for …, 2021 - Elsevier
Toxoplasmosis is caused by Toxoplasma gondii, an apicomplexan parasite that is able to
infect any nucleated cell in any warm-blooded animal. Toxoplasma gondii infects around 2 …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies

GM Alexandre-Silva, PA Brito-Souza, ACS Oliveira… - Acta Tropica, 2018 - Elsevier
The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its
mechanism still remains with relevant controversies. Some studies defend that early …

How does toxoplasmosis affect the maternal‐foetal immune interface and pregnancy?

M Borges, T Magalhães Silva, C Brito… - Parasite …, 2019 - Wiley Online Library
Toxoplasma gondii is a zoonotic parasite which, depending on the geographical location,
can infect between 10% and 90% of humans. Infection during pregnancy may result in …

Repurposing the antibacterial agents peptide 19-4LF and peptide 19-2.5 for treatment of cutaneous leishmaniasis

R El-Dirany, C Fernández-Rubio, J Peña-Guerrero… - Pharmaceutics, 2022 - mdpi.com
The lack of safe and cost-effective treatments against leishmaniasis highlights the urgent
need to develop improved leishmanicidal agents. Antimicrobial peptides (AMPs) are an …

Chemokines: A key driver for inflammation in protozoan infection

R Chauhan, M Tiwari, A Chaudhary… - International Reviews …, 2024 - Taylor & Francis
Chemokines belong to the group of small proteins within the cytokine family having strong
chemo-attractant properties. In most cases, the strong immuno-modulatory role of …

[HTML][HTML] Chemokines in Leishmaniasis: Map of cell movements highlights the landscape of infection and pathogenesis

FF de Araújo, MF Costa-Silva, AAS Pereira, FD Rêgo… - Cytokine, 2021 - Elsevier
Pathogen interactions with the host immune response components are critical for
establishing protective immunity and pathological responses against Leishmania parasites …

[HTML][HTML] Increased neutrophil derived chemokines (CXCL10 and CCL2) in human trichinellosis as possible serological markers of the polarization of the immune …

F Bruschi, B Pinto, P Fallahi, SM Ferrari, A Antonelli - Cytokine, 2023 - Elsevier
Trichinella britovi is a widely distributed parasitic nematode, transmitted through ingestion of
raw or poorly cooked meat containing muscle larvae. This helminth can regulate the host …

Cluster analysis of splenocyte microRNAs in the pig reveals key signal regulators of immunomodulation in the host during acute and chronic Toxoplasma gondii …

Z Hou, H Zhang, K Xu, S Zhu, L Wang, D Su, J Liu… - Parasites & …, 2022 - Springer
Background Toxoplasma gondii is an obligate intracellular protozoan parasite that can
cause a geographically widespread zoonosis. Our previous splenocyte microRNA profile …

Promising aryl selenoate derivatives as antileishmanial agents and their effects on gene expression

C Fernández-Rubio, M Rubio-Hernández… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Leishmaniasis remains one of the main public health problems worldwide, with special
incidence in the poorest populations. Selenium and its derivatives can be potent therapeutic …