Role of mTOR signaling in female reproduction
Z Guo, Q Yu - Frontiers in endocrinology, 2019 - frontiersin.org
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase of the
phosphatidylinositol kinase-related kinase family that regulates cell growth, metabolism, and …
phosphatidylinositol kinase-related kinase family that regulates cell growth, metabolism, and …
Research progress of endometrial receptivity in patients with polycystic ovary syndrome: a systematic review
X Bai, L Zheng, D Li, Y Xu - Reproductive biology and endocrinology, 2021 - Springer
Polycystic ovary syndrome (PCOS) is a neuroendocrine heterogeneous disease that
frequently occurs in women of reproductive age, causing serious damage to the fertility …
frequently occurs in women of reproductive age, causing serious damage to the fertility …
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation
R Hua, Y Wang, W Lian, W Li, Y Xi, S Xue, T Kang… - Gene, 2021 - Elsevier
The extracellular vesicles (EVs) of uterine flushing fluids (UFs) mediate intrauterine
communication between conceptus and uterus in pigs. The small RNAs of UFs-EVs are …
communication between conceptus and uterus in pigs. The small RNAs of UFs-EVs are …
[HTML][HTML] The effect of dexamethasone on uterine receptivity, mediated by the ERK1/2-mTOR pathway, and the implantation window: An experimental study
Materials and Methods In this experimental study, 40 BALB/c female mice aged eight wk old
weighing approximately 25.0±1.4 gr were used. The mice were divided into four groups (n …
weighing approximately 25.0±1.4 gr were used. The mice were divided into four groups (n …
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells
B Wang, M Gao, Y Yao, H Shen, H Li, J Sun… - Reproductive Biology …, 2024 - Springer
Inadequate endometrial receptivity often results in embryo implantation failure and
miscarriage. Human chorionic gonadotropin (hCG) is a key signaling molecule secreted …
miscarriage. Human chorionic gonadotropin (hCG) is a key signaling molecule secreted …
The Multiple Functions of HB-EGF in Female Reproduction and Related Cancer: Molecular Mechanisms and Targeting Strategies
Y Zhang, L Tang, H Liu, Y Cheng - Reproductive Sciences, 2024 - Springer
Heparin-binding growth factor (HB-EGF) is a member of the epidermal growth factor (EGF)
ligand family which has a crucial role in women's health. However, there is a lack of …
ligand family which has a crucial role in women's health. However, there is a lack of …
Focusing on the role of protein kinase mTOR in endometrial physiology and pathology: insights for therapeutic interventions
B Wang, M Gao, Y Yao, H Li, X Zhang - Molecular Biology Reports, 2024 - Springer
The mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase crucial for
cellular differentiation, proliferation, and autophagy. It shows a complex role in the …
cellular differentiation, proliferation, and autophagy. It shows a complex role in the …
miR223‐3p, HAND2, and LIF expression regulated by calcitonin in the ERK1/2‐mTOR pathway during the implantation window in the endometrium of mice
B Niknafs, MB Hesam Shariati… - American Journal of …, 2021 - Wiley Online Library
Problem Approximately one‐third of infertility cases are related to the female partner, and
implantation failure is the primary reason for female infertility. The current research was …
implantation failure is the primary reason for female infertility. The current research was …
Electroacupuncture improves endometrial receptivity through miRNA-223-3p-mediated regulation of leukemia inhibitory factor/signal transducer and activator of …
F You, X Du, T Zhang, Y Wang, Y Lv, L Zeng - Bioengineered, 2022 - Taylor & Francis
Ovulation-inducing drugs such as endogenous steroids could reduce endometrial receptivity
during the implantation window, resulting in lower clinical pregnancy rates and higher …
during the implantation window, resulting in lower clinical pregnancy rates and higher …
mTOR signaling and endometrial receptivity in infertile women with intramural uterine leiomyomas
A Makker, MM Goel, D Nigam, I Makker… - Middle East Fertility …, 2023 - Springer
Background Receptive endometrium is a restraining factor in the establishment of
pregnancy in several estrogen-dependent gynecological disorders including uterine …
pregnancy in several estrogen-dependent gynecological disorders including uterine …