Osteoarthritis: pathology, diagnosis, and treatment options

B Abramoff, FE Caldera - Medical Clinics, 2020 - medical.theclinics.com
Osteoarthritis (OA) is endemic throughout the world. An estimated 30.8 million adults in the
United States and 300 million individuals worldwide are living with OA. 1, 2 It is the leading …

The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part two: strengthening exercise programs

L Brosseau, J Taki, B Desjardins… - Clinical …, 2017 - journals.sagepub.com
Objective: To identify effective strengthening exercise programs and provide rehabilitation
teams and patients with updated, high-quality recommendations concerning traditional land …

Animal models of chronic pain: advances and challenges for clinical translation

NE Burma, H Leduc‐Pessah, CY Fan… - Journal of …, 2017 - Wiley Online Library
Chronic pain is a global problem that has reached epidemic proportions. An estimated 20%
of adults suffer from pain, and another 10% are diagnosed with chronic pain each year …

[HTML][HTML] Mesenchymal stem cells in osteoarthritis therapy: a review

C Zhu, W Wu, X Qu - American journal of translational research, 2021 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a chronic joint disease that generally occurs worldwide with pain and
disability. The progression is slow, and it is mostly diagnosed midlife and often disturbs the …

Multicenter randomized sham controlled study of genicular artery embolization for knee pain secondary to osteoarthritis

S Bagla, R Piechowiak, A Sajan, J Orlando… - Journal of Vascular and …, 2022 - Elsevier
Purpose To assess the safety and efficacy of genicular artery embolization (GAE) compared
with a sham procedure in the treatment of knee pain secondary to mild to moderate …

Clinical outcomes of transcatheter arterial embolisation for chronic knee pain: mild-to-moderate versus severe knee osteoarthritis

SH Lee, JH Hwang, DH Kim, YH So, J Park… - CardioVascular and …, 2019 - Springer
Purpose This retrospective study was conducted to compare the clinical outcomes of
transcatheter arterial embolisation for chronic knee pain in patients with mild-to-moderate …

[HTML][HTML] Osteochondral tissue chip derived from iPSCs: modeling OA pathologies and testing drugs

Z Lin, Z Li, EN Li, X Li, CJ Del Duke, H Shen… - … in bioengineering and …, 2019 - frontiersin.org
Osteoarthritis (OA) is a chronic disease mainly characterized by degenerative changes in
cartilage, but other joint elements such as bone are also affected. To date, there are no …

[HTML][HTML] Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration

S Ashraf, BH Cha, JS Kim, J Ahn, I Han, H Park… - Osteoarthritis and …, 2016 - Elsevier
Adult articular chondrocytes undergo slow senescence and dedifferentiation during in vitro
expansion, restricting successful cartilage regeneration. A complete understanding of the …

Curcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled …

S Srivastava, AK Saksena, S Khattri, S Kumar… - …, 2016 - Springer
Background and purpose Curcuma longa L.(CL), an Indian herb, has been used to treat
many disorders because of its wide spectrum of pharmacological activities. It has been …

[HTML][HTML] Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis

S Sirong, C Yang, T Taoran, L Songhang, L Shiyu… - Bone research, 2020 - nature.com
Osteoarthritis, a disorder characterized by articular cartilage deterioration, varying degrees
of inflammation, and chondrocyte apoptosis, is the most common chronic joint disease. To …