Connecting chemistry and biology through molecular descriptors
A Fernández-Torras, A Comajuncosa-Creus… - Current Opinion in …, 2022 - Elsevier
Through the representation of small molecule structures as numerical descriptors and the
exploitation of the similarity principle, chemoinformatics has made paramount contributions …
exploitation of the similarity principle, chemoinformatics has made paramount contributions …
Recent trends in detecting, controlling, and detoxifying of patulin mycotoxin using biotechnology methods
GL Ngolong Ngea, Q Yang, R Castoria… - … Reviews in Food …, 2020 - Wiley Online Library
Patulin (PAT) is a mycotoxin that can contaminate many foods and especially fruits and fruit‐
based products. Therefore, accurate and effective testing is necessary to enable producers …
based products. Therefore, accurate and effective testing is necessary to enable producers …
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
Multi‐omics datasets can provide molecular insights beyond the sum of individual omics.
Various tools have been recently developed to integrate such datasets, but there are limited …
Various tools have been recently developed to integrate such datasets, but there are limited …
Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque
Biomedical data is accumulating at a fast pace and integrating it into a unified framework is a
major challenge, so that multiple views of a given biological event can be considered …
major challenge, so that multiple views of a given biological event can be considered …
[HTML][HTML] Periodontal treatment and microbiome-targeted therapy in management of periodontitis-related nonalcoholic fatty liver disease with oral and gut dysbiosis
R Kuraji, T Shiba, TS Dong, Y Numabe… - World journal of …, 2023 - ncbi.nlm.nih.gov
A growing body of evidence from multiple areas proposes that periodontal disease,
accompanied by oral inflammation and pathological changes in the microbiome, induces gut …
accompanied by oral inflammation and pathological changes in the microbiome, induces gut …
[HTML][HTML] Predicting and understanding the response to short-term intensive insulin therapy in people with early type 2 diabetes
YON Lopez, R Retnakaran, B Zinman, RE Pratley… - Molecular …, 2019 - Elsevier
Objective Short-term intensive insulin therapy (IIT) early in the course of type 2 diabetes
acutely improves beta-cell function with long-lasting effects on glycemic control. However …
acutely improves beta-cell function with long-lasting effects on glycemic control. However …
[HTML][HTML] Footprint-based functional analysis of multiomic data
A Dugourd, J Saez-Rodriguez - Current Opinion in Systems Biology, 2019 - Elsevier
Omic technologies allow us to generate extensive data, including transcriptomic, proteomic,
phosphoproteomic and metabolomic. These data can be used to study signal transduction …
phosphoproteomic and metabolomic. These data can be used to study signal transduction …
LINT‐web: a web‐based lipidomic data mining tool using intra‐Omic integrative correlation strategy
F Li, J Song, Y Zhang, S Wang, J Wang, L Lin… - Small …, 2021 - Wiley Online Library
Lipidomics is a younger member of the “omics” family. It aims to profile lipidome alterations
occurring in biological systems. Similar to the other “omics”, lipidomic data is highly …
occurring in biological systems. Similar to the other “omics”, lipidomic data is highly …
Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle
Systemic metabolic homeostasis is regulated by inter-organ metabolic cycles involving
multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic …
multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic …
Signaling and gene expression in skeletal muscles in type 2 diabetes: current results and OMICS perspectives
AV Vorotnikov, DV Popov, PA Makhnovskii - Biochemistry (Moscow), 2022 - Springer
Skeletal muscles mainly contribute to the emergence of insulin resistance, impaired glucose
tolerance and the development of type 2 diabetes. Molecular mechanisms that regulate …
tolerance and the development of type 2 diabetes. Molecular mechanisms that regulate …