Vitamin D, referring to the two forms, D2 from the diet and D3 primarily derived from
phototransformation in the skin, is a prohormone important in human health. The most …

Due to its high degree of contagiousness and like almost no other virus, SARS-CoV-2 has
put the health of the world population on alert. COVID-19 can provoke an acute inflammatory …

The genomic actions of the vitamin D are mediated via its biologically most potent metabolite
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …

Vitamin D is currently one of the hottest topics in research and clinics, as well as in everyday
life. Over the past decades, scientists gathered overwhelming evidence indicating that the …

We tested whether novel CYP11A1-derived vitamin D 3-and lumisterol-hydroxyderivatives,
including 1, 25 (OH) 2 D 3, 20 (OH) D 3, 1, 20 (OH) 2 D 3, 20, 23 (OH) 2 D 3, 1, 20, 23 (OH) 3 …

Vitamin D receptor (VDR) mediates many genomic and non-genomic effects of vitamin D.
Recently, the mitochondrial effects of vitamin D have been characterized in many cell types …

A novel pathway of vitamin D activation by CYP11A has previously been elucidated. To
define the mechanism of action of its major dihydroxy-products, we tested the divergence …

Psoriasis is a systemic, chronic, immune-mediated disease that affects approximately 2–3%
of the world's population. The etiology and pathophysiology of psoriasis are still unknown …

Ultraviolet B (UVB), in addition to having carcinogenic activity, is required for the production
of vitamin D3 (D3) in the skin which supplies> 90% of the body's requirement. Vitamin D is …

The classical pathway of vitamin D activation follows the sequence D3→ 25 (OH) D3→ 1, 25
(OH) 2 D3 with the final product acting on the receptor for vitamin D (VDR). An alternative …