Energy-based tissue fusion for sutureless closure: applications, mechanisms, and potential for functional recovery

EA Kramer, ME Rentschler - Annual Review of Biomedical …, 2018 - annualreviews.org
As minimally invasive surgical techniques progress, the demand for efficient, reliable
methods for vascular ligation and tissue closure becomes pronounced. The surgical …

[HTML][HTML] An ex vivo preliminary investigation into the impact of parameters on tissue welding strength in small intestine mucosa-mucosa end-to-end anastomosis

C Zhu, L Yin, J Xu, H Liu, X Xiang, H Zhao… - … in Bioengineering and …, 2023 - frontiersin.org
Background: Tissue welding is an electrosurgical technique that can fuse tissue for small
intestine anastomosis. However, limited knowledge exists on its application in mucosa …

[HTML][HTML] Alterations in detrusor contractility in rat model of bladder cancer

IB Philyppov, GV Sotkis, A Rock, M Roudbaraki… - Scientific Reports, 2020 - nature.com
Urinary incontinence of idiopathic nature is a common complication of bladder cancer, yet,
the mechanisms underlying changes in bladder contractility associated with cancer are not …

Contribution of transient receptor potential vanilloid 1 (TRPV1) channel to cholinergic contraction of rat bladder smooth muscle

BR Sharopov, IB Philyppov, SI Yeliashov… - The Journal of …, 2024 - Wiley Online Library
Transient receptor potential vanilloid 1 (TRPV1) is a calcium‐permeable ion channel that is
gated by the pungent constituent of red chili pepper, capsaicin, and by related chemicals …

Comparison of a New High-Frequency Electric Welding System for Intestinal Closure with Hand-Sewn In Vivo Pig Model

S Han, Z Cai, X Ning, L He, J Chen… - … & Advanced Surgical …, 2015 - liebertpub.com
Background: Various surgical small intestinal anastomosis methods are in current use, but
improvements are always desired. Thus, we compared the feasibility, effectiveness, and …

TRPA1-dependent regulation of bladder detrusor smooth muscle contractility in normal and type I diabetic rats

IB Philyppov, ON Paduraru, KL Gulak… - Journal of Smooth …, 2016 - jstage.jst.go.jp
Abstract TRPA1 is a Ca2+-permeable cation channel that is activated by painful low
temperatures (˂ 17 C), irritating chemicals, reactive metabolites and mediators of …

[HTML][HTML] Temperature-dependent contractility of rat tunica dartos muscle: Contribution of cold, menthol-sensitive TRPM8

IB Philyppov, GV Sotkis, BR Sharopov, AO Danshyna… - BBA advances, 2023 - Elsevier
Tunica dartos smooth muscle (TDSM) lies beneath the scrotal skin, and its contraction leads
to scrotum wrinkling upon cooling. However, neither the nature of TDSM cold-sensitivity nor …

Influence of skin effect on current flow through electrodes of electro-surgical instruments and biological tissue

V Sydorets, A Dubko, O Bondarenko… - 2016 15th Biennial …, 2016 - ieeexplore.ieee.org
An algorithm was developed for solving two-dimensional axially symmetric elliptic problems
of skin effect modeling in a two-phase medium (electrode-biological tissue). The numerical …

Myorelaxant action of fluorine-containing pinacidil analog, flocalin, in bladder smooth muscle is mediated by inhibition of L-type calcium channels rather than …

IB Philyppov, AА Golub, OI Boldyriev… - Naunyn-Schmiedeberg's …, 2016 - Springer
Flocalin (FLO) is a new ATP-sensitive K+(K ATP) channel opener (KCO) derived from
pinacidil (PIN) by adding fluorine group to the drug's structure. FLO acts as a potent …

Impairment of cholinergic bladder contractility in rat model of type I diabetes complicated by cystitis: Contribution of neurotransmitter-degrading ectoenzymes

IA Vladimirova, IB Philyppov, GV Sotkis… - European Journal of …, 2019 - Elsevier
Parasympathetic regulation of urinary bladder contractions primarily involves acetylcholine
release and activation of detrusor smooth muscle (DSM) muscarinic acetylcholine (mACh) …