Recent policy changes have led to significant increases in the use of cannabis for both
medical and recreational purposes. Although men are more likely to endorse past month …

The purpose of this review is to discuss ways to think about and study sex differences in
preclinical animal models. We use the framework of addiction, in which animal models have …

Decades of research have examined the effects of cannabis on neurocognition. Recent
advances in this field provide us with a better understanding of how cannabis use influences …

In the last 25 years data has grown exponentially dealing with the discovery of the
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …

BACKGROUND: To examine gender differences among individuals diagnosed with DSM-IV
lifetime cannabis use disorder (CUD). METHODS: A nationally representative sample of US …

Human and animal research indicates the presence of sex differences in drug abuse. These
data suggest that females, compared to males, are more vulnerable to key phases of the …

Gender-dependent differences in the rate of initiation and frequency of misuse of addicting
drugs have been widely described. Yet, men and women also differ in their propensity to …

Marijuana is the most widely used illicit drug in the US, and marijuana use by women is on
the rise. Women have been found to be more susceptible to the development of cannabinoid …

Rationale Animal studies have found robust sex differences in the pharmacokinetics and
pharmacodynamics of Δ 9-tetrahydrocannabinol (THC). However, the human evidence …

Abstract Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is
responsible for the drug's reinforcing effects. Retrospective human studies suggest that …