[HTML][HTML] Field-flow fractionation in molecular biology and biotechnology

S Giordani, V Marassi, A Placci, A Zattoni, B Roda… - Molecules, 2023 - mdpi.com
Field-flow fractionation (FFF) is a family of single-phase separative techniques exploited to
gently separate and characterize nano-and microsystems in suspension. These techniques …

Sorting Technology for Mesenchymal Stem Cells from a Single Tissue Source

X Feng, F Qi, H Wang, W Li, Y Gan, C Qi, Z Lin… - Stem Cell Reviews and …, 2024 - Springer
Mesenchymal stem cells (MSCs) are adult stem cells that can be obtained, enriched and
proliferated in vitro. They owned enormous potential in fields like regenerative medicine …

[HTML][HTML] Scalable mesenchymal stem cell enrichment from bone marrow aspirate using deterministic lateral displacement (DLD) microfluidic sorting

NTK Zen, KK Zeming, KL Teo, M Loberas, J Lee… - Lab on a Chip, 2023 - pubs.rsc.org
The growing interest in regenerative medicine has opened new avenues for novel cell
therapies using stem cells. Bone marrow aspirate (BMA) is an important source of stromal …

[HTML][HTML] Deubiquitinating enzyme USP7 is required for self-renewal and multipotency of human bone marrow-derived mesenchymal stromal cells

YJ Kim, KH Park, KM Lee, YM Chun… - International journal of …, 2022 - mdpi.com
Ubiquitin-specific protease 7 (USP7) is highly expressed in a variety of malignant tumors.
However, the role of USP7 in regulating self-renewal and differentiation of human bone …

[HTML][HTML] Celector®: An Innovative Technology for Quality Control of Living Cells

S Zia, B Roda, A Maggio, P Marrazzo, V Pizzuti… - Applied Sciences, 2022 - mdpi.com
Among the in vitro and ex vivo models used to study human cancer biology, cancer cell lines
are widely utilized. The standardization of a correct tumor model including the stage of in …

[HTML][HTML] Emerging technologies for quality control of cell-based, advanced therapy medicinal products

S Zia, V Pizzuti, F Paris, F Alviano, L Bonsi… - … of Pharmaceutical and …, 2024 - Elsevier
Advanced therapy medicinal products (ATMP) are complex medicines based on gene
therapy, somatic cell therapy, and tissue engineering. These products are rapidly arising as …

[HTML][HTML] The Medium Obtained from the Culture of Hodgkin Lymphoma Cells Affects the Biophysical Characteristics of a Fibroblast Cell Model

M Rossi, F Alviano, B Myrtaj, S Zia, S Righi, V Pizzuti… - Bioengineering, 2023 - mdpi.com
The neoplastic Hodgkin-Reed-Sternberg (HRS) cells in Hodgkin lymphoma (HL) represent
only 1–10% of cells and are surrounded by an inflammatory microenvironment. The HL …

[HTML][HTML] Perinatal Stem Cell Therapy to Treat Type 1 Diabetes Mellitus: A Never-Say-Die Story of Differentiation and Immunomodulation

F Paris, V Pizzuti, P Marrazzo, A Pession… - International Journal of …, 2022 - mdpi.com
Human term placenta and other postpartum-derived biological tissues are promising
sources of perinatal cells with unique stem cell properties. Among the massive current …

Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate using Deterministic Lateral Displacement (DLD) Microfluidics Sorting

NT Kwan Zen, KZ Kwek, TK Leng, M Loberas, J Lee… - bioRxiv, 2023 - biorxiv.org
The growing interest in regenerative medicine has opened new avenues for novel cell
therapies using stem cells. Bone Marrow Aspirate (BMA) is an important source of stromal …