[HTML][HTML] A tough act to follow: Collagen hydrogel modifications to improve mechanical and growth factor loading capabilities

SO Sarrigiannidis, JM Rey, O Dobre… - Materials Today Bio, 2021 - Elsevier
Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Biomedical applications of DNA‐based hydrogels

J Gačanin, CV Synatschke… - Advanced Functional …, 2020 - Wiley Online Library
Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …

A MgFe‐LDH nanosheet‐incorporated smart thermo‐responsive hydrogel with controllable growth factor releasing capability for bone regeneration

Z Lv, T Hu, Y Bian, G Wang, Z Wu, H Li, X Liu… - Advanced …, 2023 - Wiley Online Library
Although growth factor (GF)‐loaded hydrogels have been explored as promising materials
in repairing bone defects, it still remains challenging to construct smart hydrogels with …

Engineering platelet‐rich plasma based dual‐network hydrogel as a bioactive wound dressing with potential clinical translational value

X Zhang, D Yao, W Zhao, R Zhang, B Yu… - Advanced Functional …, 2021 - Wiley Online Library
Delayed wound healing has a profound impact on patients, healthcare, and society. Platelet‐
rich plasma (PRP) gel, as a preparation for regenerative medicine, has proven to be of …

Advancing models of neural development with biomaterials

JG Roth, MS Huang, TL Li, VR Feig, Y Jiang… - Nature Reviews …, 2021 - nature.com
Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

Managing diabetic foot ulcers: pharmacotherapy for wound healing

D Dixon, M Edmonds - Drugs, 2021 - Springer
Historically, there has been a scarcity of evidence-based topical therapy to hasten the
healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged …

Angiogenesis in tissue engineering: as nature intended?

V Mastrullo, W Cathery, E Velliou… - … in bioengineering and …, 2020 - frontiersin.org
Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation

Z Zhang, B Sha, L Zhao, H Zhang, J Feng… - Nature …, 2022 - nature.com
During mesenchymal development, the sources of mechanical forces transduced by cells
transition over time from predominantly cell-cell interactions to predominantly cell …

Decellularized extracellular matrix for remodeling bioengineering organoid's microenvironment

L Zhu, J Yuhan, H Yu, B Zhang, K Huang, L Zhu - Small, 2023 - Wiley Online Library
Over the past decade, stem cell‐and tumor‐derived organoids are the most promising
models in developmental biology and disease modeling, respectively. The matrix is one of …

[HTML][HTML] Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging

M Liu, L Wang, Y Lo, SCC Shiu, AB Kinghorn… - Cells, 2022 - mdpi.com
A wide variety of nanomaterials have emerged in recent years with advantageous properties
for a plethora of therapeutic and diagnostic applications. Such applications include drug …