Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …

Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Glycoproteomics is a powerful yet analytically challenging research tool. Software packages
aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but …

Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …

Recent advances in methods for enrichment and mass spectrometric analysis of intact
glycopeptides have produced large-scale glycoproteomics datasets, but interpreting these …

Site-specific characterization of glycosylation requires intact glycopeptide analysis, and
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …

Protein glycosylation is a highly important, yet poorly understood protein post-translational
modification. Thousands of possible glycan structures and compositions create potential for …

Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Protein glycosylation, one of the most heterogeneous post-translational modifications, can
play a major role in cellular signal transduction and disease progression. Traditional mass …