EGeRepDR: An enhanced genetic-based representation learning for drug repurposing using multiple biomedical sources
S Muniyappan, AXA Rayan, GT Varrieth - Journal of Biomedical Informatics, 2023 - Elsevier
Motivation Drug repurposing (DR) is an imminent approach for identifying novel therapeutic
indications for the available drugs and discovering novel drugs for previously untreatable …
indications for the available drugs and discovering novel drugs for previously untreatable …
Total network controllability analysis discovers explainable drugs for Covid-19 treatment
Background The active pursuit of network medicine for drug repurposing, particularly for
combating Covid-19, has stimulated interest in the concept of structural controllability in …
combating Covid-19, has stimulated interest in the concept of structural controllability in …
Network crosstalk as a basis for drug repurposing
D Guala, ELL Sonnhammer - Frontiers in Genetics, 2022 - frontiersin.org
The need for systematic drug repurposing has seen a steady increase over the past decade
and may be particularly valuable to quickly remedy unexpected pandemics. The abundance …
and may be particularly valuable to quickly remedy unexpected pandemics. The abundance …
Drug Repurposing: Strategies and Study Design for Bringing Back Old Drugs to the Mainline
A Schcolnik-Cabrera - The Quintessence of Basic and Clinical Research …, 2023 - Springer
Every year, the success rate of the development of new medications covering different fields
of human health gets more limited. This is particularly challenging for conditions imposing a …
of human health gets more limited. This is particularly challenging for conditions imposing a …
[PDF][PDF] Total Controllability Analysis Discovers Explainable Drugs for Covid-19 Therapy and Prevention
X Wei, C Pan, X Zhang, W Zhang - CoRR, 2022 - researchgate.net
Network medicine has been actively pursued lately for repurposing drugs for Covid-19. One
such approach adopts structural controllability, a theory developed for controlling a network …
such approach adopts structural controllability, a theory developed for controlling a network …
Illuminating the chemical space of therapeutical relevance: from pharmaceutical patents to untargeted proteins
MJ Falaguera Mata - 2022 - tdx.cat
Systems pharmacology is the discipline that studies the so-called 'pharmacological
space'with a holistic and network-based perspective. Its challenge is to shed light on the …
space'with a holistic and network-based perspective. Its challenge is to shed light on the …
[PDF][PDF] Network Crosstalk as a Basis for Drug Repurposing. Front. Genet. 13: 792090. doi: 10.3389/fgene. 2022.792090
D Guala, ELL Sonnhammer - Frontiers in Genetics| www …, 2022 - scienceopen.com
The need for systematic drug repurposing has seen a steady increase over the past decade
and may be particularly valuable to quickly remedy unexpected pandemics. The abundance …
and may be particularly valuable to quickly remedy unexpected pandemics. The abundance …