Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity
In conjugate, inactivated, recombinant, and toxoid vaccines, adjuvants are extensively and
essentially used for enhanced and long-lasting protective immune responses. Depending …
essentially used for enhanced and long-lasting protective immune responses. Depending …
[HTML][HTML] Advancements in vaccine adjuvants: The journey from alum to nano formulations
Vaccination is a groundbreaking approach in preventing and controlling infectious diseases.
However, the effectiveness of vaccines can be greatly enhanced by the inclusion of …
However, the effectiveness of vaccines can be greatly enhanced by the inclusion of …
Mesoporous silica nanoparticles: synthesis, pharmaceutical applications, biodistribution, and biosafety assessment
Mesoporous silica nanoparticles (MSNs) are a key example of the innovation in material
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …
Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development
N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …
soluble recombinant antigens by stronger protective immunogenicity associated with the …
Traditional and new influenza vaccines
SS Wong, RJ Webby - Clinical microbiology reviews, 2013 - Am Soc Microbiol
The challenges in successful vaccination against influenza using conventional approaches
lie in their variable efficacy in different age populations, the antigenic variability of the …
lie in their variable efficacy in different age populations, the antigenic variability of the …
Virosome-based nanovaccines; a promising bioinspiration and biomimetic approach for preventing viral diseases: A review
Vaccination is the most effective means of controlling infectious disease-related morbidity
and mortality. However, due to low immunogenicity of viral antigens, nanomedicine as a …
and mortality. However, due to low immunogenicity of viral antigens, nanomedicine as a …
Developments in vaccine adjuvants
FZ Firdaus, M Skwarczynski, I Toth - Vaccine Design: Methods and …, 2022 - Springer
Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …
Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery
Vaccines have been at the forefront of improving human health for over two centuries. The
challenges faced in developing effective vaccines flow from complexities associated with the …
challenges faced in developing effective vaccines flow from complexities associated with the …
Freeze-drying: A flourishing strategy to fabricate stable pharmaceutical and biological products
KK Abla, MM Mehanna - International journal of pharmaceutics, 2022 - Elsevier
Freeze-drying (FD) of nanoparticles, microorganisms, genes, and vaccines is an auspicious
technique used to enhance long-term stability and facilitate transportation mainly for …
technique used to enhance long-term stability and facilitate transportation mainly for …
Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges
Summary Human immunodeficiency virus (HIV)-1 is mainly transmitted mucosally during
sexual intercourse. We therefore evaluated the protective efficacy of a vaccine active at …
sexual intercourse. We therefore evaluated the protective efficacy of a vaccine active at …