Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma

AA Dar, V Bezrookove, M Nosrati… - Proceedings of the …, 2022 - National Acad Sciences
Therapy of BRAF-mutant melanoma with selective inhibitors of BRAF (BRAFi) and MEK
(MEKi) represents a major clinical advance but acquired resistance to therapy has emerged …

[HTML][HTML] ADS-J21 is a novel HIV-1 entry inhibitor targeting gp41

R Liang, D Dou, C Wang, S Huo, Y Wu, J Wang… - Current Research in …, 2024 - Elsevier
HIV-1 envelope glycoprotein gp41 mediates fusion between HIV-1 and host cell
membranes, making inhibitors of gp41 attractive anti-HIV drugs. We previously reported an …