Design of heme enzymes with a tunable substrate binding pocket adjacent to an open metal coordination site
The catalytic versatility of pentacoordinated iron is highlighted by the broad range of natural
and engineered activities of heme enzymes such as cytochrome P450s, which position a …
and engineered activities of heme enzymes such as cytochrome P450s, which position a …
Bioexcitons by design: How do we get there?
M Reppert - The Journal of Physical Chemistry B, 2023 - ACS Publications
Biological pigment–protein complexes (PPCs) exhibit a remarkable ability to tune the optical
properties of biological excitons (bioexcitons) through specific pigment–protein interactions …
properties of biological excitons (bioexcitons) through specific pigment–protein interactions …
An expandable, modular de novo protein platform for precision redox engineering
The electron-conducting circuitry of life represents an as-yet untapped resource of exquisite,
nanoscale biomolecular engineering. Here, we report the characterization and structure of a …
nanoscale biomolecular engineering. Here, we report the characterization and structure of a …
Harvesting electrons and holes from photodriven symmetry-breaking charge separation within a perylenediimide photosynthetic model dimer
JM Bradley, AF Coleman, PJ Brown… - Proceedings of the …, 2023 - National Acad Sciences
Understanding how to utilize symmetry-breaking charge separation (SB-CS) offers a path
toward increasingly efficient light-harvesting technologies. This process plays a central role …
toward increasingly efficient light-harvesting technologies. This process plays a central role …
[HTML][HTML] De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs
Natural photosystems couple light harvesting to charge separation using a “special pair” of
chlorophyll molecules that accepts excitation energy from the antenna and initiates an …
chlorophyll molecules that accepts excitation energy from the antenna and initiates an …
Photovoltaic enzymes by design and evolution
The global energy crisis challenges us to develop more efficient strategies for the
sustainable production of energy. Given the excellent efficiency of the natural photosynthetic …
sustainable production of energy. Given the excellent efficiency of the natural photosynthetic …
Structural and Mechanistic Studies of the Type IIS Restriction Endonuclease PaqCI and De Novo Designed Circular Tandem Repeat Proteins
MA Kennedy - 2023 - search.proquest.com
This thesis spans the work completed on two parallel projects, to (i) study the structure and
mechanism of the Type IIS restriction endonuclease PaqCI, and (ii) participate in the …
mechanism of the Type IIS restriction endonuclease PaqCI, and (ii) participate in the …