Cytopathogenesis and inhibition of host gene expression by RNA viruses
DS Lyles - Microbiology and molecular biology reviews, 2000 - Am Soc Microbiol
Many viruses interfere with host cell function in ways that are harmful or pathological. This
often results in changes in cell morphology referred to as cytopathic effects. However …
often results in changes in cell morphology referred to as cytopathic effects. However …
Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus
The compartmentalization of DNA replication and gene transcription in the nucleus and
protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus …
protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus …
Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitro
ME Clark, PM Lieberman, AJ Berk… - Molecular and cellular …, 1993 - Taylor & Francis
Host cell RNA polymerase II (Pol II)-mediated transcription is inhibited by poliovirus
infection. This inhibition is correlated to a specific decrease in the activity of a …
infection. This inhibition is correlated to a specific decrease in the activity of a …
Causes and implications of codon usage bias in RNA viruses
IS Belalov, AN Lukashev - PloS one, 2013 - journals.plos.org
Choice of synonymous codons depends on nucleotide/dinucleotide composition of the
genome (termed mutational pressure) and relative abundance of tRNAs in a cell …
genome (termed mutational pressure) and relative abundance of tRNAs in a cell …
Inhibition of host cell transcription by poliovirus: cleavage of transcription factor CREB by poliovirus-encoded protease 3Cpro
P Yalamanchili, U Datta, A Dasgupta - Journal of virology, 1997 - Am Soc Microbiol
Host cell RNA polymerase II-mediated transcription is inhibited by poliovirus infection.
Previous studies from our laboratory showed that activated transcription from a cyclic AMP …
Previous studies from our laboratory showed that activated transcription from a cyclic AMP …
Poliovirus proteinase 3C converts an active form of transcription factor IIIC to an inactive form: a mechanism for inhibition of host cell polymerase III transcription by …
ME Clark, T Hämmerle, E Wimmer, A Dasgupta - The EMBO journal, 1991 - embopress.org
In HeLa cells, RNA polymerase III (pol III)‐mediated transcription is severely inhibited by
poliovirus infection. This is due primarily to a reduction in the transcriptional activity of TFIIIC …
poliovirus infection. This is due primarily to a reduction in the transcriptional activity of TFIIIC …
The interaction of cytoplasmic RNA viruses with the nucleus
MK Weidman, R Sharma, S Raychaudhuri, P Kundu… - Virus research, 2003 - Elsevier
Mammalian cells infected with poliovirus, the prototype member of the picornaviridae family,
undergo rapid macromolecular and metabolic changes resulting in efficient replication and …
undergo rapid macromolecular and metabolic changes resulting in efficient replication and …
Inhibition of basal transcription by poliovirus: a virus-encoded protease (3Cpro) inhibits formation of TBP-TATA box complex in vitro
P Yalamanchili, K Harris, E Wimmer… - Journal of virology, 1996 - Am Soc Microbiol
Host cell RNA polymerase II (pol II)-mediated transcription is inhibited by poliovirus infection.
We demonstrate here that both TATA-and initiator-mediated basal transcription is inhibited …
We demonstrate here that both TATA-and initiator-mediated basal transcription is inhibited …
Foot-and-mouth disease virus protease 3C inhibits cellular transcription and mediates cleavage of histone H3
M Tesar, O Marquardt - Virology, 1990 - Elsevier
Foot-and-mouth disease virus protease 3C is essential for the processing of the viral
precursor polyprotein. It is shown here to also inhibit gene expression in baby hamster …
precursor polyprotein. It is shown here to also inhibit gene expression in baby hamster …
Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation
RJ White, D Stott, PWJ Rigby - Cell, 1989 - cell.com
B2 genes are rodent-specific middle repetitive elements transcribed by RNA polymerase Ill.
They are expressed in the ectoderm and mesoderm but not in the embryonic or …
They are expressed in the ectoderm and mesoderm but not in the embryonic or …