Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

According to the WHO, 38 million individuals were living with human immunodeficiency virus
(HIV), 25.4 million of which were using antiretroviral therapy (ART) at the end of 2019 …

Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …

A frequent mechanism for drug-induced liver injury (DILI) is the formation of reactive
metabolites that trigger hepatitis through direct toxicity or immune reactions. Both events …

The treatment of metabolic disease is becoming an increasingly important component of the
long-term management of patients with well controlled HIV on antiretroviral therapy (ART) …

Nonalcoholic fatty liver disease (NAFLD) affects 25% of adults in the general population and
is a disease spectrum ranging from steatosis to nonalcoholic steatohepatitis (NASH) to end …

With the advent of antiretroviral therapy (ART), HIV‐infected individuals are now living
longer and healthier lives. However, ART does not completely restore health and treated …

Advances in antiretroviral therapy (ART) have transformed infection with human
immunodeficiency virus (HIV) into a chronic illness, in which the majority of persons living …

HIV infection and antiretroviral therapy (ART) treatment exert diverse effects on adipocytes
and stromal-vascular fraction cells, leading to changes in adipose tissue quantity …

Genome integrity is critical for proper cell functioning, and chromosome instability can lead
to age-related diseases, including cancer and neurodegenerative disorders. Chromosome …