Acquired immunity to malaria
Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …
exposed to Plasmodium falciparum infection from severe disease and death. There is no …
Variant surface antigens of Plasmodium falciparum and their roles in severe malaria
Proliferation and differentiation inside erythrocytes are important steps in the life cycle of
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …
Discovery of gene function by expression profiling of the malaria parasite life cycle
KG Le Roch, Y Zhou, PL Blair, M Grainger, JK Moch… - Science, 2003 - science.org
The completion of the genome sequence for Plasmodium falciparum, the species
responsible for most malaria human deaths, has the potential to reveal hundreds of new …
responsible for most malaria human deaths, has the potential to reveal hundreds of new …
A host-targeting signal in virulence proteins reveals a secretome in malarial infection
Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte,
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
Malaria parasite proteins that remodel the host erythrocyte
Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
Antigenic Variation in Plasmodium falciparum
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …
proliferation in its host depends on the successive expression of variant molecules at the …
Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity
Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …
Sticking for a cause: the falciparum malaria parasites cytoadherence paradigm
After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …