Our understanding of diabetes mellitus has benefited from a combination of clinical
investigations and work in model organisms and cell lines. Organoid models for a wide …

Stimulator of interferon genes (STING) is a crucial innate immune sensor responsible for
distinguishing pathogens and cytosolic DNA, mediating innate immune signaling pathways …

Insulin resistance and β-cell dysfunction are two main molecular bases yet to be further
elucidated for type 2 diabetes (T2D). Accumulating evidence indicates that stimulator of …

Lipotoxic injury of pancreatic β cells is an important pathological feature in type 2 diabetes
mellitus (T2DM). Stimulator of interferon genes (STING) can recognize its own DNA leaked …

Maternal low-protein diet (LP) throughout gestation affects pancreatic β-cell fraction of the
offspring at birth, thus increasing their susceptibility to metabolic dysfunction and type 2 …

Pancreatic β-cell expansion and functional maturation during the birth-to-weaning period
plays an essential role in the adaptation of plasma insulin levels to metabolic needs. These …

The prevalence of maternal obesity is increasing in the United States. Offspring born to
women with obesity or poor glycemic control have greater odds of becoming obese and …

Epigallocatechin gallate (EGCG) has a wide consumption for its health advantages. The
current study investigates the effects of prenatal EGCG administration on glucose …

The activation of stimulator of interferon genes (STING) signalling pathway has been
suggested to promote the immune responses against malignancy. STING is activated in …

Overconsumption of energy‐rich foods that disrupt caloric balance is a fundamental cause of
overweight, obesity and diabetes. Dysglycemia and the resulting cardiovascular disease …