Inflammation is an organism's physiological response to harmful septic and aseptic stimuli.
This process begins locally through the influx of immune system cells to the damaged tissue …

Clear cell renal cell carcinoma (ccRCC), a prevalent kidney cancer form characterised by its
invasiveness and heterogeneity, presents challenges in late‐stage prognosis and treatment …

The monocyte chemoattractant protein-induced protein (MCPIP) family consists of 4
members (MCPIP1–4) encoded by the ZC3h12A-D genes, which are located at different loci …

Simple Summary Growing tumors induce an immune response. For proper immune
response, both CD8+ and CD4+ effector T cells are required. Tumors avoid attacks from …

ZC3H12B is the most enigmatic member of the ZC3H12 protein family. The founding
member of this family, Regnase-1/MCPIP1/ZC3H12A, is a well-known modulator of …

Abstract Background and Aims The study investigates the practical utility of whole-blood
gene expression profiling to diagnose inflammatory bowel diseases [IBDs]. Methods The …

Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause
of death worldwide. Patient‐derived xenograft (PDX) models maintain complex intratumoral …

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer. It is
highly vascularized and largely resistant to traditional chemo-and radiotherapy. Decreases …

Obesity is considered a serious chronic disease, associated with an increased risk of
developing cardiovascular diseases, non-alcoholic fatty liver disease and type 2 diabetes …

The precise physiological functions and mechanisms regulating RNase Regnase‐2 (Reg‐
2/ZC3H12B/MCPIP2) activity remain enigmatic. We found that Reg‐2 actively modulates …