Clinical applications of stem cell-derived exosomes

F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

[HTML][HTML] Programming assembly of biomimetic exosomes: an emerging theranostic nanomedicine platform

X Xu, L Xu, C Wen, J Xia, Y Zhang, Y Liang - Materials Today Bio, 2023 - Elsevier
Exosomes have emerged as a promising cell-free therapeutic approach. However,
challenges in large-scale production, quality control, and heterogeneity must be overcome …

Tumor-targeted exosomes for delivery of anticancer drugs

R Raguraman, D Bhavsar, D Kim, X Ren, V Sikavitsas… - Cancer letters, 2023 - Elsevier
Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …

Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

Exosome-like systems: nanotechnology to overcome challenges for targeted cancer therapies

J García-Fernández, M de la Fuente Freire - Cancer Letters, 2023 - Elsevier
Exosomes are natural extracellular nanovesicles (30–150 nm in diameter) with the ability to
interact with and be taken up by specific cells. They are being explored as delivery systems …

Plant-derived exosomes: a green approach for cancer drug delivery

S Madhan, R Dhar, A Devi - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs). In the current
decade, they have been highlighted for cancer therapeutic development. Cancer is a global …

Dendritic cell-derived exosomes in cancer immunotherapy

S Luo, J Chen, F Xu, H Chen, Y Li, W Li - Pharmaceutics, 2023 - mdpi.com
Exosomes are nanoscale vesicles released by diverse types of cells for complex
intercellular communication. Numerous studies have shown that exosomes can regulate the …

Role of exosomes in epithelial–mesenchymal transition

B Bhattacharya, S Nag, S Mukherjee… - ACS Applied Bio …, 2023 - ACS Publications
Epithelial–mesenchymal transition (EMT) is a fundamental process driving cancer
metastasis, transforming non-motile cells into a motile population that migrates to distant …

Digging the intercellular crosstalkviaextracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?

A Macedo-Pereira, C Martins, J Lima… - … Clinics and Research, 2023 - journals.lww.com
Glioblastoma (GBM) is an adult's most aggressive brain tumor. The advances in molecular
pathology and cell signaling pathways have deepened researchers' understanding of …

Impact of exosome therapy on pancreatic cancer and its progression

M El-Tanani, H Nsairat, II Matalka, AAA Aljabali… - Medical Oncology, 2023 - Springer
Pancreatic cancer, one of the most aggressive tumors, has a dismal prognosis because of
the low rates of early identification, fast progression, difficulties following surgery, and the …