Antibody-based affinity capture has become the gold standard in sample preparation for
determination of low-abundance protein biomarkers in biological matrices prior to liquid …

Currently, three recombinant antigens based vaccines are under clinical trials against
Schistosomiasis, but there is no vaccine available for prophylaxis or therapeutic. This study …

Protein acetylation is a post-translational modification regulating diverse cellular processes.
By using proteomic approaches, we identified N-terminal and ε-lysine acetylated proteins in …

Schistosomiasis (also known as bilharzia) is a neglected tropical disease caused by
platyhelminths of the genus Schistosoma. The disease is endemic in tropical and subtropical …

Pathogenic species of Leptospira cause leptospirosis, a bacterial zoonotic disease with a
global distribution affecting over one million people annually. Reservoir hosts of …

Trichophyton rubrum is the most common fungal pathogen in the world, which has been
studied as an important dermatophyte model organism. Despite the prevalence of T. rubrum …

Mekong schistosomiasis caused by Schistosoma mekongi is a public health problem that
occurs along the border between southern Laos and northern Cambodia. Given its restricted …

Background Novel anti-schistosomal multi-stage drugs are needed because only a single
drug, praziquantel, is available for the treatment of schistosomiasis and is poorly effective on …

Background The heterologous expression of parasitic proteins is challenging because the
sequence composition often differs significantly from host preferences. However, the …

血吸虫病是一种被忽视的人兽共患寄生虫病. 目前, 吡喹酮是治疗血吸虫病的首选药物,
也是治疗日本血吸虫病的唯一有效药物. 自20 世纪70 年代问世以来, 吡喹酮已在大规模血吸虫 …