Bidirectional relationships of comorbidity with obstructive sleep apnoea

M Gleeson, WT McNicholas - European respiratory review, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is frequently associated with comorbidities that include
metabolic, cardiovascular, renal, pulmonary and neuropsychiatric. There is considerable …

New perspectives for mucolytic, anti-inflammatory and adjunctive therapy with 1, 8-cineole in COPD and asthma: review on the new therapeutic approach

LJ Juergens, H Worth, UR Juergens - Advances in therapy, 2020 - Springer
Abstract The mucolytic monoterpene 1, 8-cineole (eucalyptol), the major constituent of
eucalyptus species, is well known for its anti-inflammatory, antioxidant, bronchodilatory …

COPD-OSA overlap syndrome: evolving evidence regarding epidemiology, clinical consequences, and management

WT McNicholas - Chest, 2017 - Elsevier
COPD and OSA are both highly prevalent, which implies that both disorders occurring
together (overlap syndrome) is likely to be common based on chance association alone …

OSA and chronic respiratory disease: mechanisms and epidemiology

BW Locke, JJ Lee, KM Sundar - International Journal of Environmental …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications
on the outcomes of patients with chronic lung disease. The hallmark of OSA is a collapse of …

Inherent vs. induced loop gain abnormalities in obstructive sleep apnea

N Deacon-Diaz, A Malhotra - Frontiers in Neurology, 2018 - frontiersin.org
Unstable ventilatory chemoreflex control, quantified as loop gain, is recognized as one of
four key pathophysiological traits that contribute to cause obstructive sleep apnea (OSA) …

[HTML][HTML] Comorbid obstructive sleep apnoea and chronic obstructive pulmonary disease and the risk of cardiovascular disease

WT McNicholas - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA)
syndrome are both highly prevalent, affecting at least 10% of the general adult population …

Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway

J Song, L Jiang, C Fu, X Wu, Z Liu, L Xie… - Acta Pharmacologica …, 2020 - nature.com
Oxidative stress caused by chronic intermittent hypoxia (CIH) is the hallmark of obstructive
sleep apnea (OSA). Among the first line of defense against oxidative stress is the …

Sleep-disordered breathing and chronic respiratory infections: A narrative review in adult and pediatric population

P Faverio, U Zanini, A Monzani, G Parati… - International Journal of …, 2023 - mdpi.com
Sleep-disordered breathing (SDB) comprises different diseases characterized by abnormal
respiratory patterns during sleep including obstructive sleep apnea. SDB prevalence and …

Obstructive Sleep Apnea-Associated Intermittent Hypoxia-Induced Immune Responses in Males, Pregnancies, and Offspring

R Song, TL Baker, JJ Watters, S Kumar - International Journal of …, 2024 - mdpi.com
Obstructive sleep apnea (OSA), a respiratory sleep disorder associated with cardiovascular
diseases, is more prevalent in men. However, OSA occurrence in pregnant women rises to a …

Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

G Wu, YY Lee, EM Gulla, A Potter, J Kitzmiller… - Elife, 2021 - elifesciences.org
Obstructive sleep apnea (OSA) results from episodes of airway collapse and intermittent
hypoxia (IH) and is associated with a host of health complications. Although the lung is the …