African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Harnessing ancient genomes to study the history of human adaptation

S Marciniak, GH Perry - Nature Reviews Genetics, 2017 - nature.com
The past several years have witnessed an explosion of successful ancient human genome-
sequencing projects, with genomic-scale ancient DNA data sets now available for more than …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

[HTML][HTML] Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

M Hajdinjak, F Mafessoni, L Skov, B Vernot, A Hübner… - Nature, 2021 - nature.com
Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

The genomic history of the Iberian Peninsula over the past 8000 years

I Olalde, S Mallick, N Patterson, N Rohland… - Science, 2019 - science.org
We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

S Fan, JP Spence, Y Feng, MEB Hansen, J Terhorst… - Cell, 2023 - cell.com
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12
indigenous African populations. We identify millions of unreported variants, many predicted …

Ancient DNA indicates human population shifts and admixture in northern and southern China

MA Yang, X Fan, B Sun, C Chen, J Lang, YC Ko… - Science, 2020 - science.org
Human genetic history in East Asia is poorly understood. To clarify population relationships,
we obtained genome-wide data from 26 ancient individuals from northern and southern East …

A high-coverage Neandertal genome from Vindija Cave in Croatia

K Prüfer, C De Filippo, S Grote, F Mafessoni, P Korlević… - Science, 2017 - science.org
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

The Beaker phenomenon and the genomic transformation of northwest Europe

I Olalde, S Brace, ME Allentoft, I Armit, K Kristiansen… - Nature, 2018 - nature.com
From around 2750 to 2500 bc, Bell Beaker pottery became widespread across western and
central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled …

The population history of northeastern Siberia since the Pleistocene

M Sikora, VV Pitulko, VC Sousa, ME Allentoft, L Vinner… - Nature, 2019 - nature.com
Northeastern Siberia has been inhabited by humans for more than 40,000 years but its deep
population history remains poorly understood. Here we investigate the late Pleistocene …