Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …

Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …

Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …

Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Aims Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly
recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and …

Heart failure with preserved ejection fraction (HFpEF) involves multiple pathophysiological
mechanisms, which result in the heterogeneous phenotypes that are evident clinically, and …

Background: There is no effective medical treatment for heart failure with preserved ejection
fraction (HFpEF). Increases in pulmonary capillary wedge pressure (PCWP) develop in …

Heart failure with preserved ejection fraction (HFpEF) is a complex heterogeneous disease
for which our pathophysiological understanding is still limited and specific prevention and …

Background: Cardiac reserve is depressed in patients with heart failure and preserved
ejection fraction (HFpEF). The mechanisms causing this are poorly understood. Objectives …

Aims The impact of atrial fibrillation (AF) ablation in early heart failure with preserved
ejection fraction (HFpEF) is unknown. Our aim was to determine the impact of AF ablation on …