Heart failure with preserved ejection fraction in perspective
MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap
Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …
Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction
M Obokata, YNV Reddy, SV Pislaru, V Melenovsky… - Circulation, 2017 - Am Heart Assoc
Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …
The pathophysiology of heart failure with preserved ejection fraction
BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta‐analysis
TM Gorter, ES Hoendermis… - European journal of …, 2016 - Wiley Online Library
Aims Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly
recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and …
recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and …
Biological phenotypes of heart failure with preserved ejection fraction
GA Lewis, EB Schelbert, SG Williams… - Journal of the American …, 2017 - jacc.org
Heart failure with preserved ejection fraction (HFpEF) involves multiple pathophysiological
mechanisms, which result in the heterogeneous phenotypes that are evident clinically, and …
mechanisms, which result in the heterogeneous phenotypes that are evident clinically, and …
Sodium nitrite improves exercise hemodynamics and ventricular performance in heart failure with preserved ejection fraction
BA Borlaug, KE Koepp, V Melenovsky - Journal of the American College of …, 2015 - jacc.org
Background: There is no effective medical treatment for heart failure with preserved ejection
fraction (HFpEF). Increases in pulmonary capillary wedge pressure (PCWP) develop in …
fraction (HFpEF). Increases in pulmonary capillary wedge pressure (PCWP) develop in …
Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities
I Cuijpers, SJ Simmonds, M van Bilsen… - Basic research in …, 2020 - Springer
Heart failure with preserved ejection fraction (HFpEF) is a complex heterogeneous disease
for which our pathophysiological understanding is still limited and specific prevention and …
for which our pathophysiological understanding is still limited and specific prevention and …
Myocardial injury and cardiac reserve in patients with heart failure and preserved ejection fraction
M Obokata, YNV Reddy, V Melenovsky… - Journal of the American …, 2018 - jacc.org
Background: Cardiac reserve is depressed in patients with heart failure and preserved
ejection fraction (HFpEF). The mechanisms causing this are poorly understood. Objectives …
ejection fraction (HFpEF). The mechanisms causing this are poorly understood. Objectives …
A prospective STudy using invAsive haemodynamic measurements foLLowing catheter ablation for AF and early HFpEF: STALL AF‐HFpEF
H Sugumar, S Nanayakkara, D Vizi… - European Journal of …, 2021 - Wiley Online Library
Aims The impact of atrial fibrillation (AF) ablation in early heart failure with preserved
ejection fraction (HFpEF) is unknown. Our aim was to determine the impact of AF ablation on …
ejection fraction (HFpEF) is unknown. Our aim was to determine the impact of AF ablation on …