The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

G protein–coupled receptors (GPCRs) are the largest family of cell surface receptors. Class
B1 GPCRs constitute a subfamily of 15 receptors that characteristically contain large …

In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

Like most organisms, the nematode Caenorhabditis elegans relies heavily on
neuropeptidergic signaling. This tiny animal represents a suitable model system to study …

G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic
of receptor structure. Substantial experimental evidence supports the existence of GPCR …

The Cambrian explosion was a unique animal radiation~ 540 million years ago that
produced the full range of body plans across bilaterians. The genetic mechanisms …

Abstract Background The Antarctic clam, Laternula elliptica, is an infaunal stenothermal
bivalve mollusc with a circumpolar distribution. It plays a significant role in bentho-pelagic …

Appetitive behaviors require complex decision making that involves the integration of
environmental stimuli and physiological needs. C. elegans mate searching is a male …

The type-1 parathyroid hormone receptor (PTHR1) is a family BG protein–coupled receptor
(GPCR) that mediates the actions of two polypeptide ligands; parathyroid hormone (PTH) …