RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …

Disclosures: Dr. Narazaki reported grants from JSPS KAKENHI and grants from Chugai
Pharmaceutical Co., Ltd. during the conduct of the study; personal fees from Mitsubishi …

Abstract N 6-Methyladenosine (m6A) RNA modification is present in messenger RNAs
(mRNA), ribosomal RNAs (rRNA), and spliceosomal RNAs (snRNA) in humans. Although …

Dysregulated inflammation is a central pathological process in diverse disease states.
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …

In considering an overview of microRNA biology, it is useful to consider microRNAs as a part
of cellular communication. At the simplest level, microRNAs act to decrease the expression …

MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …

Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …

Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and
transmitted between mammalian cells via extracellular vesicles (EVs), including endosome …

MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …