tRNA transfers to the limelight
AK Hopper, EM Phizicky - Genes & development, 2003 - genesdev.cshlp.org
1Department of Biochemistry and Molecular Biology, Pennsylvania State University College
of Medicine, Hershey, Pennsylvania 17033, USA; 2Department of Biochemistry and …
of Medicine, Hershey, Pennsylvania 17033, USA; 2Department of Biochemistry and …
Of proteins and RNA: the RNase P/MRP family
O Esakova, AS Krasilnikov - Rna, 2010 - rnajournal.cshlp.org
Nuclear ribonuclease (RNase) P is a ubiquitous essential ribonucleoprotein complex, one of
only two known RNA-based enzymes found in all three domains of life. The RNA component …
only two known RNA-based enzymes found in all three domains of life. The RNA component …
[HTML][HTML] Single-molecule mRNA decay measurements reveal promoter-regulated mRNA stability in yeast
Messenger RNA decay measurements are typically performed on a population of cells.
However, this approach cannot reveal sufficient complexity to provide information on …
However, this approach cannot reveal sufficient complexity to provide information on …
snoRNPs: functions in ribosome biogenesis
Ribosomes are perhaps the most critical macromolecular machine as they are tasked with
carrying out protein synthesis in cells. They are incredibly complex structures composed of …
carrying out protein synthesis in cells. They are incredibly complex structures composed of …
Comparison of preribosomal RNA processing pathways in yeast, plant and human cells–focus on coordinated action of endo‐and exoribonucleases
Proper regulation of ribosome biosynthesis is mandatory for cellular adaptation, growth and
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …
Ribonuclease P: the evolution of an ancient RNA enzyme
SC Walker, DR Engelke - Critical reviews in biochemistry and …, 2006 - Taylor & Francis
ABSTRACT Ribonuclease P (RNase P) is an ancient and essential endonuclease that
catalyses the cleavage of the 5′ leader sequence from precursor tRNAs (pre-tRNAs). The …
catalyses the cleavage of the 5′ leader sequence from precursor tRNAs (pre-tRNAs). The …
Ribosomopathies: Global process, tissue specific defects
PC Yelick, PA Trainor - Rare Diseases, 2015 - Taylor & Francis
Disruptions in ribosomal biogenesis would be expected to have global and in fact lethal
effects on a developing organism. However, mutations in ribosomal protein genes have …
effects on a developing organism. However, mutations in ribosomal protein genes have …
RNase MRP Cleaves the CLB2 mRNA To Promote Cell Cycle Progression: Novel Method of mRNA Degradation
T Gill, T Cai, J Aulds, S Wierzbicki… - Molecular and cellular …, 2004 - Taylor & Francis
RNase mitochondrial RNA processing (RNase MRP) mutants have been shown to have an
exit-from-mitosis defect that is caused by an increase in CLB2 mRNA levels, leading to …
exit-from-mitosis defect that is caused by an increase in CLB2 mRNA levels, leading to …
Ribosome synthesis meets the cell cycle
C Dez, D Tollervey - Current opinion in microbiology, 2004 - Elsevier
A large number of ribosome synthesis factors have been identified using proteomic analyses
in yeast. The patterns of RNA and protein co-precipitation suggest that ribosome synthesis …
in yeast. The patterns of RNA and protein co-precipitation suggest that ribosome synthesis …
Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator
The growth of an individual is deeply influenced by the regulation of cell growth and division,
both of which also contribute to a wide variety of pathological conditions, including cancer …
both of which also contribute to a wide variety of pathological conditions, including cancer …