The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome
from single cells is transforming our understanding of cell biology in health and disease. In …

Visualization of the cellular heterogeneity and spatial architecture of the tumor
microenvironment (TME) is becoming increasingly important to understand mechanisms of …

To acquire a deeper understanding of electrochemical systems requires techniques that
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …

Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …

High-throughput single-cell profiling provides an unprecedented ability to uncover the
molecular states of millions of cells. These technologies are, however, destructive to cells …

By providing spatial, molecular and morphological data over time, live-cell imaging can
provide a deeper understanding of the cellular and signalling events that determine cancer …

Understanding and predicting molecular responses in single cells upon chemical, genetic or
mechanical perturbations is a core question in biology. Obtaining single-cell measurements …

The “epigenetics” concept was first described in 1942. Thus far, chemical modifications on
histones, DNA, and RNA have emerged as three important building blocks of epigenetic …

The growing clinical success of hematopoietic stem/progenitor cell (HSPC) gene therapy
(GT) relies on the development of viral vectors as portable" Trojan horses" for safe and …

Diffusion Schrödinger bridges (DSBs) have recently emerged as a powerful framework for
recovering stochastic dynamics via their marginal observations at different time points …