Targeting inflammation in atherosclerosis—from experimental insights to the clinic

O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

Clinical application of intermittent fasting for weight loss: progress and future directions

KA Varady, S Cienfuegos, M Ezpeleta… - Nature Reviews …, 2022 - nature.com
Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

Calorie restriction with or without time-restricted eating in weight loss

D Liu, Y Huang, C Huang, S Yang, X Wei… - … England Journal of …, 2022 - Mass Medical Soc
Background The long-term efficacy and safety of time-restricted eating for weight loss are not
clear. Methods We randomly assigned 139 patients with obesity to time-restricted eating …

Randomized controlled trial for time-restricted eating in healthy volunteers without obesity

Z Xie, Y Sun, Y Ye, D Hu, H Zhang, Z He… - Nature …, 2022 - nature.com
Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial

DA Lowe, N Wu, L Rohdin-Bibby, AH Moore… - JAMA internal …, 2020 - jamanetwork.com
Importance The efficacy and safety of time-restricted eating have not been explored in large
randomized clinical trials. Objective To determine the effect of 16: 8-hour time-restricted …

Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: a randomized clinical trial

H Jamshed, FL Steger, DR Bryan… - JAMA internal …, 2022 - jamanetwork.com
Importance It is unclear how effective intermittent fasting is for losing weight and body fat,
and the effects may depend on the timing of the eating window. This randomized trial …

Intermittent fasting and metabolic health

I Vasim, CN Majeed, MD DeBoer - Nutrients, 2022 - mdpi.com
Given the ongoing strain that the obesity epidemic has placed on public health outcomes,
new and effective approaches to weight control are needed. One approach to improving …

[HTML][HTML] Effects of 4-and 6-h time-restricted feeding on weight and cardiometabolic health: a randomized controlled trial in adults with obesity

S Cienfuegos, K Gabel, F Kalam, M Ezpeleta… - Cell metabolism, 2020 - cell.com
Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …

Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health: Physiological and pathophysiological …

M Narici, GD Vito, M Franchi, A Paoli… - European journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic is an unprecedented health crisis as entire populations have been
asked to self-isolate and live in home-confinement for several weeks to months, which in …

Cancer metabolism: phenotype, signaling and therapeutic targets

JH Park, WY Pyun, HW Park - Cells, 2020 - mdpi.com
Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as
aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis …