[HTML][HTML] Engineering customized nanovaccines for enhanced cancer immunotherapy

J Guo, C Liu, Z Qi, T Qiu, J Zhang, H Yang - Bioactive Materials, 2024 - Elsevier
Nanovaccines have gathered significant attention for their potential to elicit tumor-specific
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …

Components, formulations, deliveries, and combinations of tumor vaccines

T Liu, W Yao, W Sun, Y Yuan, C Liu, X Liu, X Wang… - ACS …, 2024 - ACS Publications
Tumor vaccines, an important part of immunotherapy, prevent cancer or kill existing tumor
cells by activating or restoring the body's own immune system. Currently, various …

Lymph-targeted high-density lipoprotein-mimetic nanovaccine for multi-antigenic personalized cancer immunotherapy

M Liu, Y Feng, Y Lu, R Huang, Y Zhang, Y Zhao… - Science …, 2024 - science.org
Cancer vaccines show huge potential for cancer prevention and treatment. However, their
efficacy remains limited due to weak immunogenicity regarding inefficient stimulation of …

A Biomimetic Autophagosomes‐Based Nanovaccine Boosts Anticancer Immunity

L Qu, G Cui, Y Sun, R Ye, Y Sun, F Meng… - Advanced …, 2024 - Wiley Online Library
Personalized cancer vaccines based on tumor cell lysates offer promise for cancer
immunotherapy yet fail to elicit a robust therapeutic effect due to the weak immunogenicity of …

Boosting Theranostic Performance of AIEgens Using Nanocatalyzer for Robust Cancer Immunotherapy

Y Li, Z Du, Y Zhang, X Kang, J Song… - Advanced Functional …, 2024 - Wiley Online Library
High‐performance theranostic systems are of paramount importance for achieving precise
image‐guided cancer immunotherapy. Here, a novel nanoplatform is presented that …

A dual enhancing strategy of novel nanovaccine based on TIM3 silencing nanoadjuvants and desialylated cancer cell membrane antigens for personalized …

K Li, X Li, J Wu, H Wu, M Wu, Y Zhou… - Advanced Functional …, 2024 - Wiley Online Library
Cancer vaccines represent a promising form of immunotherapy employed in the treatment of
cancer. However, their efficiency in eliciting immune responses is limited, and satisfactory …

Cancer cell membrane proteins-encapsulated nanovaccine enhances cancer immunotherapy and prevention by provoking antigen-specific cellular immunity via the …

X Luo, X Chen, R Ma, Z Fu, Z Liu, Q Su, H Fu… - Chemical Engineering …, 2024 - Elsevier
Cancer nanovaccines offer a promising strategy for fighting against tumors, however, the
engineering of cancer nanovaccines that can be easily fabricated with tanglesome cancer …

Hybrid nanoparticle–mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines

J Li, T Wu, W Wang, Y Gong, M Lu, M Zhang, W Lu… - Science …, 2024 - science.org
In situ vaccine (ISV) is a versatile and personalized local immunotherapeutic strategy.
However, the compromised viability and function of dendritic cells (DCs) in a tumor …

Hydrogel activation of Mincle receptors for tumor cell processing: A novel approach in cancer immunotherapy

J Lin, Y Zhou, C Li, B Li, H Hao, F Tian, H Li, Z Liu… - Biomaterials, 2024 - Elsevier
An obstacle in current tumor immunotherapies lies in the challenge of achieving sustained
and tumor-targeting T cell immunity, impeded by the limited antigen processing and cross …

Cancer nanovaccines: nanomaterials and clinical perspectives

N Desai, V Chavda, TRR Singh, ND Thorat, LK Vora - Small, 2024 - Wiley Online Library
Cancer nanovaccines represent a promising frontier in cancer immunotherapy, utilizing
nanotechnology to augment traditional vaccine efficacy. This review comprehensively …