Fermented foods in the management of obesity: Mechanisms of action and future challenges

M Jalili, M Nazari, F Magkos - International journal of molecular sciences, 2023 - mdpi.com
Fermented foods are part of the staple diet in many different countries and populations and
contain various probiotic microorganisms and non-digestible prebiotics. Fermentation is the …

TLR4 is a link between diabetes and Alzheimer's disease

NQ Huang, H Jin, S Zhou, J Shi, F Jin - Behavioural brain research, 2017 - Elsevier
Recently, more and more studies have shown that there is an essential link between
diabetes mellitus (DM) and Alzheimer's disease (AD). In addition, innate immunity plays an …

Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children

A Nier, AJ Engstler, IB Maier, I Bergheim - PLoS One, 2017 - journals.plos.org
Background & aims Recent studies have shown that patients with manifest non-alcoholic
fatty liver disease (NAFLD), eg steatosis grade 3 or steatohepatitis with or without beginning …

Toll-like receptor 4: a promising crossroads in the diagnosis and treatment of several pathologies

MM Garcia, C Goicoechea, M Molina-Álvarez… - European Journal of …, 2020 - Elsevier
Abstract Toll-like receptor 4 (TLR4) is expressed in a wide variety of cells and is the central
component of the mammalian innate immune system. Since its discovery in 1997, TLR4 has …

Emerging evidence of Toll-like receptors as a putative pathway linking maternal inflammation and neurodevelopmental disorders in human offspring: A systematic …

VX Han, HF Jones, S Patel, SS Mohammad… - Brain, behavior, and …, 2022 - Elsevier
Inflammation is increasingly recognised to play a major role in gene-environment
interactions in neurodevelopmental disorders (NDDs). The effects of aberrant immune …

[HTML][HTML] Particulate matter exposure is associated with inflammatory gene methylation in obese subjects

L Cantone, S Iodice, L Tarantini, B Albetti… - Environmental …, 2017 - Elsevier
Background Overweight and obesity are becoming more widespread with alarming
projections for the coming years. Obesity may increase susceptibility to the adverse effects of …

Acute strenuous exercise induces an imbalance on histone H4 acetylation/histone deacetylase 2 and increases the proinflammatory profile of PBMC of obese …

GP Dorneles, MCR Boeira, LL Schipper… - Oxidative Medicine …, 2017 - Wiley Online Library
This study evaluated the response of global histone H4 acetylation (H4ac), histone
deacetylase 2 (HDAC2) activity, as well as the production of proinflammatory cytokines and …

Differential expression of human peripheral mononuclear cells phenotype markers in type 2 diabetic patients and type 2 diabetic patients on metformin

MS Al Dubayee, H Alayed, R Almansour… - Frontiers in …, 2018 - frontiersin.org
Background: Although peripheral blood mononuclear cells (PBMC) have been
demonstrated to be in a pro-inflammatory state in obesity and type 2 Diabetes Mellitus …

Cornuside, by regulating the AGEs‐RAGE‐IκBα‐ERK1/2 signaling pathway, ameliorates cognitive impairment associated with brain aging

L Yu, R Che, W Zhang, J Xu, W Lian, J He… - Phytotherapy …, 2023 - Wiley Online Library
Anti‐Alzheimer's disease (AD) drugs can only change the symptoms of cognitive impairment
in a short time but cannot prevent or completely cure AD. Thus, a more effective drug is …

Adrenergic regulation of macrophage-mediated innate/inflammatory responses in obesity and exercise in this condition: role of β2 adrenergic receptors

E Ortega, I Gálvez… - Endocrine, Metabolic & …, 2019 - ingentaconnect.com
Background: The effects of exercise on the innate/inflammatory immune responses are
crucially mediated by catecholamines and adrenoreceptors; and mediations in both …