The development of vaccines, which prime the immune system to respond to future
infections, has led to global declines in morbidity and mortality from dreadful infectious …

Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

Background With the expanding applications of mass cytometry in medical research, a wide
variety of clustering methods, both semi-supervised and unsupervised, have been …

High‐dimensional single‐cell data has become an important tool in unraveling the
complexity of the immune system and its involvement in homeostasis and a large array of …

Developing new influenza vaccines with improved performance and easier administration
routes hinges on defining correlates of protection. Vaccine-elicited cellular correlates of …

Vaccinating women in pregnancy (ie, maternal immunization) has emerged as a promising
tool to tackle infant morbidity and mortality worldwide. This approach nurtures a 'gift of …

Vaccines represent one of the major advances of modern medicine. Despite the many
successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” …

Heterogeneity in vaccine response, particularly in vulnerable populations like the elderly,
represents a significant public health challenge. We conducted an in-depth examination of …

Introduction: Emerging infectious diseases are a major threat to public health, and while
vaccines have proven to be one of the most effective preventive measures for infectious …

Vaccination reduces morbidity and mortality due to infections, but efficacy may be limited
due to distinct immunogenicity at the extremes of age. This raises the possibility of …