The ultimate goal of radiation oncology is to eradicate tumours without toxicity to non-
malignant tissues. FLASH radiotherapy, or the delivery of ultra-high dose rates of radiation …

Ultrahigh–dose rate FLASH radiotherapy (FLASH-RT) is a potentially paradigm-shifting
treatment modality that holds the promise of expanding the therapeutic index for nearly any …

Importance To our knowledge, there have been no clinical trials of ultra-high-dose-rate
radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human …

Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy.
Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic …

FLASH radiotherapy (RT) is a novel technique in which the ultrahigh dose rate (UHDR)(≥
40 Gy/s) is delivered to the entire treatment volume. Recent outcomes of in vivo studies …

Simple Summary FLASH radiotherapy is a treatment technique of interest that involves
radiation delivered at ultra-high dose rates> 100 times faster than traditional radiation …

A reemergence of research implementing radiation delivery at ultra-high dose rates
(UHDRs) has triggered intense interest in the radiation sciences and has opened a new field …

Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising
innovations over the past decade in the field of radiation oncology, with the potential to …

Purpose The FLASH effect designates normal tissue sparing by ultra-high dose rate (UHDR)
compared with conventional dose rate irradiation without compromising tumor control …

Purpose To establish a beam monitoring and dosimetry system to enable the FLASH dose
rate carbon ion irradiation and investigate, at different oxygen concentrations, the in vitro …