Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis

RJ Reiter, SA Rosales-Corral, DX Tan… - International journal of …, 2017 - mdpi.com
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

[HTML][HTML] Melatonin for the prevention and treatment of cancer

Y Li, S Li, Y Zhou, X Meng, JJ Zhang, DP Xu, HB Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
The epidemiological studies have indicated a possible oncostatic property of melatonin on
different types of tumors. Besides, experimental studies have documented that melatonin …

Melatonin and cancer hallmarks

WH Talib - Molecules, 2018 - mdpi.com
Melatonin is a natural indoleamine produced by the pineal gland that has many functions,
including regulation of the circadian rhythm. Many studies have reported the anticancer …

Role and therapeutic potential of melatonin in various type of cancers

S Gurunathan, M Qasim, MH Kang… - OncoTargets and …, 2021 - Taylor & Francis
Cancer is a large group of diseases and the second leading cause of death worldwide.
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …

Association between night-shift work and cancer risk: updated systematic review and meta-analysis

A Dun, X Zhao, X Jin, T Wei, X Gao, Y Wang… - Frontiers in …, 2020 - frontiersin.org
Background: Nightshift work introduces light at night and causes circadian rhythm among
night workers, who are considered to be at increased risk of cancer. However, in the last 2 …

Melatonin: an anti‐tumor agent in hormone‐dependent cancers

J Menéndez-Menéndez… - International journal of …, 2018 - Wiley Online Library
Melatonin (N‐acetyl‐5‐methoxytryptamine) is a hormone synthesized and secreted by the
pineal gland mainly during the night, since light exposure suppresses its production. Initially …

Mechanisms underlying tumor suppressive properties of melatonin

SC Bondy, A Campbell - International journal of molecular sciences, 2018 - mdpi.com
There is considerable evidence that melatonin may be of use in the prevention and
treatment of cancer. This manuscript will review some of the human, animal and cellular …

Melatonin and cancer: A polyhedral network where the source matters

MA Bonmati-Carrion, A Tomas-Loba - Antioxidants, 2021 - mdpi.com
Melatonin is one of the most phylogenetically conserved signals in biology. Although its
original function was probably related to its antioxidant capacity, this indoleamine has been …

Melatonin inhibits EMT and PD‐L1 expression through the ERK1/2/FOSL1 pathway and regulates anti‐tumor immunity in HNSCC

X Luo, Y Chen, H Tang, H Wang, E Jiang… - Cancer …, 2022 - Wiley Online Library
Melatonin is an endogenous hormone with various biological functions and possesses anti‐
tumor properties in multiple malignancies. Immune evasion is one of the most important …

Melatonin as a promising agent to treat ovarian cancer: molecular mechanisms

LGA Chuffa, RJ Reiter, LA Lupi - Carcinogenesis, 2017 - academic.oup.com
Ovarian cancer (OC) has the highest mortality rate of all gynecological cancers, and most
patients develop chemoresistance after first-line treatments. Despite recent advances, the 5 …