Surface-enhanced Raman scattering (SERS) has emerged as a valuable technique for
molecular identification. Due to the characteristics of high sensitivity, excellent signal …

Plasmon-enhanced Raman spectroscopy (PERS), including surface-enhanced Raman
spectroscopy, shell-isolated nanoparticle-enhanced Raman spectroscopy and tip-enhanced …

Peptide–drug conjugates (PDCs) are the next generation of targeted therapeutics drug after
antibody–drug conjugates (ADCs), with the core benefits of enhanced cellular permeability …

Gold nanoparticles (GNPs) have attracted the particular attention of nanoscience and
nanoengineering due to their unique localized surface plasmonic resonance (LSPR) …

The increasing sophistication of single cell Raman spectroscopy (SCRS) via its integrations
with other advanced analytical techniques and modern data analytics, enable …

Immune checkpoint blockade (ICB) therapy has achieved remarkable success in many
cancers including melanoma. However, ICB therapy benefits only a small proportion of …

Mitochondrial redox homeostasis plays a vital role in many biological processes. Hydrogen
peroxide (H2O2), one of the most important components for the balance between oxidizing …

Cellular biomarkers mainly contain proteins, nucleic acids, glycans and many small
molecules including small biomolecule metabolites, reactive oxygen species and other …

Visualization of intracellular pH (i-pH) using surface-enhanced Raman spectroscopy (SERS)
plays an important role toward understanding of cellular processes including their …

With the development of technologies based on gold nanoparticles (AuNPs), bare AuNPs
cannot meet the increasing requirements of biomedical applications. Modifications with …