Physiological and practical effects of progesterone on reproduction in dairy cattle

MC Wiltbank, AH Souza, PD Carvalho, AP Cunha… - Animal, 2014 - cambridge.org
The discovery of progesterone (P4) and elucidation of the mechanisms of P4 action have an
important place in the history of endocrinology and reproduction. Circulating P4 …

Development of fertility programs to achieve high 21-day pregnancy rates in high-producing dairy cows

PD Carvalho, VG Santos, JO Giordano, MC Wiltbank… - Theriogenology, 2018 - Elsevier
Our objective is to overview the research that lead to the development of fertility programs for
high-producing lactating dairy cows using only GnRH and Prostaglandin F 2α (PGF 2α) …

[HTML][HTML] Effect of a second treatment with prostaglandin F2α during the Ovsynch protocol on luteolysis and pregnancy in dairy cows

MC Wiltbank, GM Baez, F Cochrane, RV Barletta… - Journal of dairy …, 2015 - Elsevier
The main objective of this study was to evaluate the effect of a second treatment with
prostaglandin F 2α (PGF) during Ovsynch on regression of the corpus luteum (CL) and on …

[HTML][HTML] New aspects of corpus luteum regulation in physiological and pathological conditions: involvement of adipokines and neuropeptides

E Mlyczyńska, M Kieżun, P Kurowska, M Dawid, K Pich… - Cells, 2022 - mdpi.com
The corpus luteum is a small gland of great importance because its proper functioning
determines not only the appropriate course of the estrous/menstrual cycle and embryo …

Perturbations in lineage specification of granulosa and theca cells may alter corpus luteum formation and function

MA Abedel-Majed, SM Romereim, JS Davis… - Frontiers in …, 2019 - frontiersin.org
Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in
mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to …

Luteinizing hormone regulation of inter-organelle communication and fate of the corpus luteum

E Przygrodzka, MR Plewes, JS Davis - International journal of molecular …, 2021 - mdpi.com
The corpus luteum is an endocrine gland that synthesizes the steroid hormone
progesterone. luteinizing hormone (LH) is a key luteotropic hormone that stimulates …

Ovarian follicular dynamics, progesterone concentrations, pregnancy rates and transcriptional patterns in Bos indicus females with a high or low antral follicle count

MA de Lima, F Morotti, BM Bayeux, RG de Rezende… - Scientific reports, 2020 - nature.com
We evaluated the effect of the antral follicle count (AFC) on ovarian follicular dynamics,
pregnancy rates, progesterone concentrations, and transcriptional patterns of genes in …

Lack of complete regression of the Day 5 corpus luteum after one or two doses of PGF2α in nonlactating Holstein cows

AB Nascimento, AH Souza, A Keskin, R Sartori… - Theriogenology, 2014 - Elsevier
The early corpus luteum (CL)(before Day 6) does not regress after a single PGF 2α
treatment. We hypothesized that increasing PGF 2α dose or number of treatments would …

Positive and negative effects of progesterone during timed AI protocols in lactating dairy cattle

MC Wiltbank, AH Souza, JO Giordano… - Animal …, 2018 - animal-reproduction.org
Circulating concentration of progesterone (P4) is determined by a balance between P4
production, primarily by corpus luteum (CL), and P4 metabolism, primarily by liver. The …

Gene expression profiling of bovine ovarian follicular and luteal cells provides insight into cellular identities and functions

SM Romereim, AF Summers, WE Pohlmeier… - Molecular and cellular …, 2017 - Elsevier
After ovulation, somatic cells of the ovarian follicle (theca and granulosa cells) become the
small and large luteal cells of the corpus luteum. Aside from known cell type-specific …