Aging is a complex natural process that leads to a decline in physiological functions, which
is visible in signs such as hair graying, thinning, and loss. Although hair graying is …

Human hair fibres are mainly comprised of proteins (> 90%) and lipids (1–9%), which are
characterised as exogenous or endogenous, depending on whether they originate from …

The stratum corneum (SC) is the outermost layer of the epidermis and plays an important
role in maintaining skin moisture and protecting the skin from the external environment …

The hair metabolome has been recognized as a valuable source of information in
pregnancy research, as it provides stable metabolite information that could assist with …

Metabolomics is a powerful tool used to understand comprehensive changes in the
metabolic response and to study the phenotype of an organism by instrumental analysis. It …

Clinical toxicology (CT) and forensic toxicology (FT) represent two disciplines of toxicology
dedicated to the qualitative and quantitative analysis and respective interpretation of …

Hair analysis has become an integral part in forensic toxicological laboratories for eg
assessment of drug or alcohol abstinence. However, hair samples can be manipulated by …

Various cosmetic hair manipulations are known to interfere with the drug of abuse
concentrations in hair. It is important to know the effects of cosmetic hair treatments as they …

Hair lipid composition varies by ethnic hair type and by hair layer. Lipids in the cuticle,
cortex, and medulla of the hair shaft provide a protective barrier to environmental and …

Over recent years, metabolomics has been featured as the state-of-the-art technology that
successfully opens the paths to understanding biological mechanisms and facilitating …