[HTML][HTML] Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-Mhigh melanoma cell populations

ML Hartman, B Talar, M Sztiller-Sikorska, D Nejc… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The activity of the M isoform of microphthalmia-associated transcription factor (MITF-M) has
been attributed to regulation of differentiation, proliferation, survival and senescence of …

[HTML][HTML] Applied diagnostics in liver cancer. Efficient combinations of sorafenib with targeted inhibitors blocking AKT/mTOR

S Llerena, N García-Díaz, S Curiel-Olmo… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths
worldwide. There is increasing interest in developing specific markers to serve as predictors …

DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity

S Sauvaigo, M Benkhiat, F Braisaz, J Girard, S Libert… - BioRxiv, 2020 - biorxiv.org
Melanoma, the most serious form of skin cancer, frequently involves the dysregulation of key
signaling pathways. Treatment strategies presently target the MAPK/ERK pathway, which is …

[HTML][HTML] Report from the II melanoma translational meeting of the Spanish Melanoma Group (GEM)

M Gonzalez-Cao, A Berrocal, S Puig… - Annals of …, 2017 - ncbi.nlm.nih.gov
Abstract The II Melanoma Translational Meeting of the Spanish Melanoma Group (GEM)
was held in Barcelona, Spain, at the Hospital Universitari Quiron-Dexeus on November 3 rd …

Cancer genomics paves the way to targeted therapy.

MÁ Piris Pinilla, N Martínez Magunacelaya… - 2015 - repositorio.unican.es
Cancer is still a mayor challenge with something more than 14M new cases per year in the
world and more of 8M patients dying yearly because of cancer. With the collaboration of …