The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm,
apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical …

Background Although machine learning (ML) algorithms have been applied to point-of-care
sepsis prognostication, ML has not been used to predict sepsis mortality in an administrative …

Patients infected with SARS-CoV-2 experience variable disease susceptibility, and patients
with comorbidities such as sepsis are often hospitalized for COVID-19 complications …

BACKGROUND Guidelines for sepsis recommend treating those at highest risk within 1
hour. The emergency care system can only achieve this if sepsis is recognised and …

Sepsis induces significant immune dysregulation characterized by lymphocyte apoptosis
and alterations in the cytokine milieu. Because cancer patients exhibit a 10-fold greater risk …

The enrichment and diversity of gut microbiota play an important role in sepsis, but the role
of gut microbiota composition and early-life colonization in sepsis and septic shock has not …

Introducción: Los antibióticos se usan con frecuencia en unidades de cuidados intensivos
(UCI). Objetivo: describir la tendencia de prescripción de antibióticos durante 8 años en …

Abstract Human apolipoprotein AI (apoA-I), the main protein of high density lipoprotein, has
been identified as a potential antimicrobial protein, which could play a role in the innate …

Despite technological advances the mortality of Multiple Organ Failure MOF (or MODS)
remains high. Liver is the main excretory organ for protein-bound toxins which accumulate in …

Sepsis is a life-threatening condition that can lead to organ dysfunction and death. Early
appropriate management based on current evidence-based practice is important. This …