Analytical and biochemical perspectives of protein O-GlcNAcylation
Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …
unique monosaccharide modification discovered in the early 1980s. With the technological …
Clip chemistry: diverse (bio)(macro) molecular and material function through breaking covalent bonds
In the two decades since the introduction of the “click chemistry” concept, the toolbox of “click
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes
Advances in chemoproteomic technology have revealed covalent interactions between
small molecules and protein nucleophiles, primarily cysteine, on a proteome-wide scale …
small molecules and protein nucleophiles, primarily cysteine, on a proteome-wide scale …
Redox-based reagents for chemoselective methionine bioconjugation
Cysteine can be specifically functionalized by a myriad of acid-base conjugation strategies
for applications ranging from probing protein function to antibody-drug conjugates and …
for applications ranging from probing protein function to antibody-drug conjugates and …
Tailored silyl ether monomers enable backbone-degradable polynorbornene-based linear, bottlebrush and star copolymers through ROMP
Ring-opening metathesis polymerization of norbornene-based (macro) monomers is a
powerful approach for the synthesis of macromolecules with diverse compositions and …
powerful approach for the synthesis of macromolecules with diverse compositions and …
Remolding and deconstruction of industrial thermosets via carboxylic acid-catalyzed bifunctional silyl ether exchange
Convenient strategies for the deconstruction and reprocessing of thermosets could improve
the circularity of these materials, but most approaches developed to date do not involve …
the circularity of these materials, but most approaches developed to date do not involve …
[HTML][HTML] Sulfenic acid chemistry, detection and cellular lifetime
V Gupta, KS Carroll - Biochimica et Biophysica Acta (BBA)-General …, 2014 - Elsevier
Background Reactive oxygen species-mediated cysteine sulfenic acid modification has
emerged as an important regulatory mechanism in cell signaling. The stability of sulfenic …
emerged as an important regulatory mechanism in cell signaling. The stability of sulfenic …
Proteome turnover in the spotlight: approaches, applications, and perspectives
In all cells, proteins are continuously synthesized and degraded to maintain protein
homeostasis and modify gene expression levels in response to stimuli. Collectively, the …
homeostasis and modify gene expression levels in response to stimuli. Collectively, the …
Thermally Robust yet Deconstructable and Chemically Recyclable High‐Density Polyethylene (HDPE)‐Like Materials Based on Si− O Bonds
AM Johnson, JA Johnson - Angewandte Chemie, 2023 - Wiley Online Library
Polyethylene (PE) is the most widely produced synthetic polymer. By installing chemically
cleavable bonds into the backbone of PE, it is possible to produce chemically …
cleavable bonds into the backbone of PE, it is possible to produce chemically …
Quantitative chemoproteomic profiling with data-independent acquisition-based mass spectrometry
Activity-based protein profiling (ABPP) has emerged as a powerful and versatile tool to
enable annotation of protein functions and discovery of targets of bioactive ligands in …
enable annotation of protein functions and discovery of targets of bioactive ligands in …